Atomistry » Chlorine » PDB 3zx3-4a7i » 3zzf
Atomistry »
  Chlorine »
    PDB 3zx3-4a7i »
      3zzf »

Chlorine in PDB 3zzf: Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase Complexed with Its Substrate N-Acetylglutamate

Enzymatic activity of Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase Complexed with Its Substrate N-Acetylglutamate

All present enzymatic activity of Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase Complexed with Its Substrate N-Acetylglutamate:
2.7.2.8;

Protein crystallography data

The structure of Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase Complexed with Its Substrate N-Acetylglutamate, PDB code: 3zzf was solved by S.De Cima, F.Gil-Ortiz, M.Crabeel, I.Fita, V.Rubio, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 2.20
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 69.701, 99.299, 190.644, 90.00, 90.00, 90.00
R / Rfree (%) 17.87 / 21.812

Other elements in 3zzf:

The structure of Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase Complexed with Its Substrate N-Acetylglutamate also contains other interesting chemical elements:

Mercury (Hg) 11 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase Complexed with Its Substrate N-Acetylglutamate (pdb code 3zzf). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 7 binding sites of Chlorine where determined in the Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase Complexed with Its Substrate N-Acetylglutamate, PDB code: 3zzf:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7;

Chlorine binding site 1 out of 7 in 3zzf

Go back to Chlorine Binding Sites List in 3zzf
Chlorine binding site 1 out of 7 in the Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase Complexed with Its Substrate N-Acetylglutamate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase Complexed with Its Substrate N-Acetylglutamate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1361

b:31.6
occ:1.00
 HG A:HG1359 1.9 41.2 0.4
CG A:ARG143 3.4 30.2 1.0
CD A:LYS170 3.6 36.2 1.0
CG A:LYS170 3.7 31.6 1.0
CB A:LYS170 3.7 29.1 1.0
CG1 A:VAL167 3.9 19.0 1.0
CD A:ARG143 4.0 34.5 1.0
CA A:VAL167 4.0 20.5 1.0
O A:VAL167 4.0 21.0 1.0
SG A:CYS171 4.2 31.3 1.0
NE A:ARG143 4.3 38.1 1.0
CB A:VAL167 4.4 20.0 1.0
CE A:LYS170 4.4 38.4 1.0
CB A:ARG143 4.4 28.1 1.0
CG2 A:VAL167 4.5 19.9 1.0
OE2 A:GLU174 4.5 39.4 1.0
C A:VAL167 4.5 20.4 1.0
N A:CYS171 4.7 25.6 1.0
CA A:LYS170 4.9 26.4 1.0
O A:ALA166 4.9 22.8 1.0
C A:LYS170 4.9 25.5 1.0

Chlorine binding site 2 out of 7 in 3zzf

Go back to Chlorine Binding Sites List in 3zzf
Chlorine binding site 2 out of 7 in the Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase Complexed with Its Substrate N-Acetylglutamate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase Complexed with Its Substrate N-Acetylglutamate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1362

b:61.5
occ:1.00
 NE2 A:GLN335 2.9 36.6 1.0
SG A:CYS119 3.1 14.3 0.5
SG A:CYS119 3.1 22.3 0.5
HG A:HG1358 3.3 33.0 0.7
O A:HOH2019 3.4 26.6 1.0
CB A:CYS119 3.4 16.2 0.5
CA A:CYS119 3.6 16.2 0.5
CA A:CYS119 3.7 17.7 0.5
CB A:GLN335 3.7 31.7 1.0
CB A:CYS119 3.8 17.8 0.5
CD A:GLN335 4.0 35.8 1.0
O A:HOH2018 4.1 22.6 1.0
CG A:GLN335 4.2 33.3 1.0
NE2 A:GLN73 4.2 36.2 1.0
CB A:PHE122 4.4 16.6 1.0
N A:CYS119 4.5 17.4 0.5
O A:CYS119 4.5 16.4 0.5
N A:CYS119 4.5 18.1 0.5
C A:CYS119 4.6 16.5 0.5
O A:CYS119 4.7 15.7 0.5
C A:CYS119 4.7 15.8 0.5
CG A:PHE122 4.7 17.0 1.0
CA A:GLN335 4.8 29.8 1.0
N A:GLN335 4.8 28.5 1.0
CD2 A:PHE122 4.9 17.9 1.0
O A:SER118 4.9 18.4 1.0
CD A:GLN73 4.9 32.5 1.0

Chlorine binding site 3 out of 7 in 3zzf

Go back to Chlorine Binding Sites List in 3zzf
Chlorine binding site 3 out of 7 in the Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase Complexed with Its Substrate N-Acetylglutamate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase Complexed with Its Substrate N-Acetylglutamate within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl1362

b:30.1
occ:1.00
 HG B:HG1360 2.7 39.5 0.5
OE1 B:GLU174 2.9 35.2 1.0
NH2 B:ARG143 3.3 31.8 1.0
CZ B:ARG143 3.3 31.8 1.0
O B:HOH2072 3.4 23.4 1.0
CL B:CL1363 3.6 10.6 1.0
O B:LYS170 3.6 20.1 1.0
NE B:ARG143 3.6 30.2 1.0
C B:LYS170 3.6 19.8 1.0
N B:CYS171 3.7 18.4 1.0
NH1 B:ARG143 3.7 33.2 1.0
CD B:GLU174 3.8 33.6 1.0
CA B:CYS171 3.9 18.8 1.0
CB B:LYS170 3.9 20.4 1.0
SG B:CYS171 4.1 22.7 1.0
CB B:GLU174 4.1 24.1 1.0
O B:HOH2071 4.4 16.1 1.0
CA B:LYS170 4.4 20.2 1.0
CD B:ARG143 4.4 28.3 1.0
OE2 B:GLU174 4.6 38.5 1.0
O B:HOH2055 4.6 17.6 1.0
CG B:GLU174 4.6 27.3 1.0
CB B:CYS171 4.6 18.1 1.0

Chlorine binding site 4 out of 7 in 3zzf

Go back to Chlorine Binding Sites List in 3zzf
Chlorine binding site 4 out of 7 in the Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase Complexed with Its Substrate N-Acetylglutamate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase Complexed with Its Substrate N-Acetylglutamate within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl1363

b:10.6
occ:1.00
 HG B:HG1360 2.3 39.5 0.5
CL B:CL1362 3.6 30.1 1.0
CD B:ARG143 3.7 28.3 1.0
CE B:LYS170 3.8 24.9 1.0
CG1 B:VAL167 4.0 13.2 1.0
CB B:LYS170 4.0 20.4 1.0
NH1 B:ARG143 4.0 33.2 1.0
CA B:VAL167 4.1 14.7 1.0
NE B:ARG143 4.2 30.2 1.0
O B:VAL167 4.2 14.8 1.0
CG B:ARG143 4.3 24.5 1.0
CZ B:ARG143 4.3 31.8 1.0
CB B:VAL167 4.4 14.5 1.0
CG2 B:VAL167 4.4 13.2 1.0
CD B:LYS170 4.5 25.3 1.0
SG B:CYS171 4.6 22.7 1.0
C B:VAL167 4.7 14.7 1.0
CB B:ARG143 4.7 21.6 1.0
NZ B:LYS170 4.7 26.8 1.0
CG B:LYS170 4.8 22.4 1.0
N B:CYS171 4.9 18.4 1.0

Chlorine binding site 5 out of 7 in 3zzf

Go back to Chlorine Binding Sites List in 3zzf
Chlorine binding site 5 out of 7 in the Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase Complexed with Its Substrate N-Acetylglutamate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase Complexed with Its Substrate N-Acetylglutamate within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl1364

b:40.3
occ:1.00
 HG B:HG1359 2.2 39.5 0.3
O B:HOH2009 3.5 16.0 1.0
O B:HOH2044 3.5 13.3 1.0
CB B:SER118 3.7 16.8 1.0
CG B:GLU115 3.8 20.6 1.0
SG B:CYS119 4.2 16.2 0.5
O B:GLU115 4.3 15.6 1.0
CA B:GLU115 4.4 17.4 1.0
OG B:SER118 4.4 18.4 1.0
CB B:GLU115 4.6 18.0 1.0
OE2 B:GLU115 4.6 26.4 1.0
CD B:GLU115 4.7 24.2 1.0
N B:CYS119 4.8 15.6 0.5
N B:CYS119 4.8 16.1 0.5
C B:GLU115 4.8 16.4 1.0
C B:SER118 5.0 16.0 1.0
CA B:SER118 5.0 16.2 1.0

Chlorine binding site 6 out of 7 in 3zzf

Go back to Chlorine Binding Sites List in 3zzf
Chlorine binding site 6 out of 7 in the Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase Complexed with Its Substrate N-Acetylglutamate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase Complexed with Its Substrate N-Acetylglutamate within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl1359

b:70.3
occ:1.00
 O C:HOH2024 2.8 14.2 1.0
SG C:CYS171 3.2 20.0 1.0
CG C:ARG143 3.3 33.5 1.0
HG C:HG1357 3.3 52.9 0.6
O C:HOH2027 3.4 15.8 1.0
OE1 C:GLU174 3.9 37.0 1.0
NE C:ARG143 4.1 39.8 1.0
CB C:ARG143 4.3 31.0 1.0
CD C:ARG143 4.4 37.1 1.0
CB C:CYS171 4.6 20.0 1.0
O C:GLN139 4.6 26.5 1.0
CD C:GLU174 4.8 34.6 1.0

Chlorine binding site 7 out of 7 in 3zzf

Go back to Chlorine Binding Sites List in 3zzf
Chlorine binding site 7 out of 7 in the Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase Complexed with Its Substrate N-Acetylglutamate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase Complexed with Its Substrate N-Acetylglutamate within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl1358

b:39.2
occ:1.00
 HG D:HG1355 2.2 42.5 0.4
O D:HOH2007 3.5 20.2 1.0
O D:HOH2040 3.6 10.5 1.0
CB D:SER118 3.8 16.7 1.0
CG D:GLU115 3.9 20.6 1.0
O D:GLU115 4.2 14.6 1.0
CA D:GLU115 4.3 17.5 1.0
SG D:CYS119 4.4 16.8 0.5
OG D:SER118 4.5 19.7 1.0
CB D:GLU115 4.6 18.4 1.0
N D:CYS119 4.7 14.8 0.5
N D:CYS119 4.7 14.9 0.5
C D:GLU115 4.8 16.0 1.0
OE2 D:GLU115 4.8 27.1 1.0
CD D:GLU115 4.9 24.0 1.0
C D:SER118 4.9 15.3 1.0
CA D:SER118 5.0 15.9 1.0

Reference:

S.De Cima, F.Gil-Ortiz, M.Crabeel, I.Fita, V.Rubio. Insight on An Arginine Synthesis Metabolon From the Tetrameric Structure of Yeast Acetylglutamate Kinase Plos One V. 7 34734 2012.
ISSN: ISSN 1932-6203
PubMed: 22529931
DOI: 10.1371/JOURNAL.PONE.0034734
Page generated: Sun Jul 21 08:41:05 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy