Chlorine in PDB 4a1n: Human Mitochondrial Endo-Exonuclease

The structure of Human Mitochondrial Endo-Exonuclease, PDB code: 4a1n was solved by M.Welin, M.Moche, C.H.Arrowsmith, H.Berglund, C.Bountra, R.Collins, A.M.Edwards, S.Flodin, S.Graslund, M.Hammarstrom, I.Johansson, T.Karlberg, T.Kotenyova, T.Nyman, C.Persson, H.Schuler, A.G.Thorsell, L.Tresaugues, J.Weigelt, P.Nordlund, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.68 / 2.80
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	103.180, 103.180, 83.890, 90.00, 90.00, 120.00
R / Rfree (%)	17.52 / 22.49

The structure of Human Mitochondrial Endo-Exonuclease also contains other interesting chemical elements:

Magnesium	(Mg)	1 atom
Sodium	(Na)	1 atom

The binding sites of Chlorine atom in the Human Mitochondrial Endo-Exonuclease (pdb code 4a1n). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Human Mitochondrial Endo-Exonuclease, PDB code: 4a1n:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Human Mitochondrial Endo-Exonuclease


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Mitochondrial Endo-Exonuclease within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1353 b:37.2 occ:1.00 N A:ILE256 3.0 21.7 1.0 O A:HOH2042 3.2 29.4 1.0 N A:TYR174 3.3 20.0 1.0 N A:GLY257 3.4 24.4 1.0 O A:ASP169 3.7 22.8 1.0 CB A:TYR174 3.8 21.7 1.0 CA A:ILE256 3.9 21.1 1.0 C A:ALA255 4.0 26.4 1.0 CA A:ALA255 4.0 21.0 1.0 CA A:GLY173 4.0 19.0 1.0 C A:ILE256 4.1 28.9 1.0 C A:ASP169 4.1 21.4 1.0 CA A:TYR174 4.1 19.6 1.0 CB A:ILE256 4.1 22.1 1.0 CA A:ASN170 4.2 16.7 1.0 C A:GLY173 4.2 24.6 1.0 CA A:GLY257 4.3 24.0 1.0 N A:ASN170 4.4 17.2 1.0 O A:GLU254 4.7 20.1 1.0 CB A:ALA255 4.7 21.5 1.0 CB A:ASP169 4.8 15.6 1.0 CG A:TYR174 4.8 24.3 1.0 N A:GLY173 4.8 20.0 1.0 CG1 A:ILE256 4.9 20.9 1.0 CD1 A:TYR174 4.9 26.7 1.0

Chlorine binding site 2 out of 2 in the Human Mitochondrial Endo-Exonuclease


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Human Mitochondrial Endo-Exonuclease within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1354 b:43.2 occ:1.00 NE A:ARG138 3.3 14.2 1.0 N A:ARG138 3.3 21.5 1.0 NH2 A:ARG138 3.5 19.2 1.0 CA A:SER137 3.7 17.2 1.0 CZ A:ARG138 3.8 28.4 1.0 CB A:ARG138 4.0 19.2 1.0 CB A:SER137 4.0 19.2 1.0 C A:SER137 4.0 23.3 1.0 CA A:ARG138 4.2 21.4 1.0 CE1 A:PHE168 4.3 13.6 1.0 CZ A:PHE168 4.3 13.1 1.0 CG A:ARG138 4.3 21.5 1.0 CD A:ARG138 4.4 15.9 1.0 O A:TRP136 4.8 17.9 1.0 O A:ARG138 4.9 26.0 1.0 N A:SER137 4.9 17.0 1.0 O A:HOH2030 5.0 22.2 1.0 CE2 A:PHE114 5.0 29.6 1.0

M.Welin, M.Moche, C.H.Arrowsmith, H.Berglund, C.Bountra, R.Collins, A.M.Edwards, S.Flodin, S.Graslund, M.Hammarstrom, I.Johansson, T.Karlberg, T.Kotenyova, T.Nyman, C.Persson, H.Schuler, A.G.Thorsell, L.Tresaugues, J.Weigelt, P.Nordlund. Human Mitochondrial Endo-Exonuclease To Be Published.