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Atomistry » Chlorine » PDB 4d0p-4da0 » 4d0x » |
Chlorine in PDB 4d0x: Pyrrole-3-Carboxamides As Potent and Selective JAK2 InhibitorsEnzymatic activity of Pyrrole-3-Carboxamides As Potent and Selective JAK2 Inhibitors
All present enzymatic activity of Pyrrole-3-Carboxamides As Potent and Selective JAK2 Inhibitors:
2.7.10.2; Protein crystallography data
The structure of Pyrrole-3-Carboxamides As Potent and Selective JAK2 Inhibitors, PDB code: 4d0x
was solved by
G.Canevari,
M.Fasolini,
J.Bertrand,
M.G.Brasca,
M.Nesi,
N.Avanzi,
D.Ballinari,
T.Bandiera,
S.Bindi,
D.Carenzi,
D.Casero,
L.Ceriani,
M.Ciomei,
A.Cirla,
M.Colombo,
S.Cribioli,
C.Cristiani,
F.Della Vedova,
G.Fachin,
E.R.Felder,
A.Galvani,
A.Isacchi,
D.Mirizzi,
I.Motto,
A.Panzeri,
E.Pesenti,
P.Vianello,
P.Gnocchi,
D.Donati,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4d0x:
The structure of Pyrrole-3-Carboxamides As Potent and Selective JAK2 Inhibitors also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Pyrrole-3-Carboxamides As Potent and Selective JAK2 Inhibitors
(pdb code 4d0x). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Pyrrole-3-Carboxamides As Potent and Selective JAK2 Inhibitors, PDB code: 4d0x: Chlorine binding site 1 out of 1 in 4d0xGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Pyrrole-3-Carboxamides As Potent and Selective JAK2 Inhibitors
![]() Mono view ![]() Stereo pair view
Reference:
M.G.Brasca,
M.Nesi,
N.Avanzi,
D.Ballinari,
T.Bandiera,
J.Bertrand,
S.Bindi,
G.Canevari,
D.Carenzi,
D.Casero,
L.Ceriani,
M.Ciomei,
A.Cirla,
M.Colombo,
S.Cribioli,
C.Cristiani,
F.Della Vedova,
G.Fachin,
M.Fasolini,
E.R.Felder,
A.Galvani,
A.Isacchi,
D.Mirizzi,
I.Motto,
A.Panzeri,
E.Pesenti,
P.Vianello,
P.Gnocchi,
D.Donati.
Pyrrole-3-Carboxamides As Potent and Selective JAK2 Inhibitors. Bioorg.Med.Chem. V. 22 4998 2014.
Page generated: Fri Jul 11 14:12:16 2025
ISSN: ISSN 0968-0896 PubMed: 25009002 DOI: 10.1016/J.BMC.2014.06.025 |
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