Atomistry » Chlorine » PDB 4e9w-4ego » 4ecl
Atomistry »
  Chlorine »
    PDB 4e9w-4ego »
      4ecl »

Chlorine in PDB 4ecl: Crystal Structure of the Cytoplasmic Domain of Vancomycin Resistance Serine Racemase Vantg

Protein crystallography data

The structure of Crystal Structure of the Cytoplasmic Domain of Vancomycin Resistance Serine Racemase Vantg, PDB code: 4ecl was solved by P.J.Stogios, Z.Wawrzak, G.Minasov, E.Evdokimova, O.Egorova, J.Cosme, R.Dileo, M.Krishnamoorthy, D.Meziane-Cherif, P.Courvalin, A.Savchenko, W.F.Anderson, Center For Structural Genomics Of Infectious Diseases(Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.91 / 2.02
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 78.682, 82.341, 117.468, 90.00, 90.14, 90.00
R / Rfree (%) 18.1 / 23.3

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of the Cytoplasmic Domain of Vancomycin Resistance Serine Racemase Vantg (pdb code 4ecl). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 8 binding sites of Chlorine where determined in the Crystal Structure of the Cytoplasmic Domain of Vancomycin Resistance Serine Racemase Vantg, PDB code: 4ecl:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Chlorine binding site 1 out of 8 in 4ecl

Go back to Chlorine Binding Sites List in 4ecl
Chlorine binding site 1 out of 8 in the Crystal Structure of the Cytoplasmic Domain of Vancomycin Resistance Serine Racemase Vantg


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Cytoplasmic Domain of Vancomycin Resistance Serine Racemase Vantg within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl401

b:24.6
occ:0.80
 NZ A:LYS125 3.0 39.2 1.0
N A:LEU133 3.3 19.9 1.0
NE2 B:GLN316 3.5 31.8 1.0
CB A:ARG132 3.5 20.6 1.0
O A:HOH593 3.6 40.9 1.0
CE A:LYS125 3.7 37.5 1.0
CB A:LEU133 3.8 17.7 1.0
SE A:MSE130 3.9 42.3 0.7
CG A:LEU133 3.9 22.1 1.0
CA A:LEU133 4.0 22.9 1.0
O A:LEU133 4.0 20.4 1.0
CD1 A:LEU133 4.1 24.0 1.0
CG A:MSE130 4.1 32.7 1.0
OE1 B:GLN316 4.3 29.5 1.0
CD B:GLN316 4.3 33.4 1.0
C A:ARG132 4.3 22.4 1.0
CA A:ARG132 4.4 22.6 1.0
C A:LEU133 4.4 25.5 1.0
CD A:ARG132 4.4 28.6 1.0
CG A:ARG132 4.5 22.8 1.0
CD A:LYS125 4.5 34.5 1.0
O A:HOH550 4.8 34.4 1.0
O A:HOH503 4.8 22.2 1.0
N A:ARG132 4.8 18.9 1.0

Chlorine binding site 2 out of 8 in 4ecl

Go back to Chlorine Binding Sites List in 4ecl
Chlorine binding site 2 out of 8 in the Crystal Structure of the Cytoplasmic Domain of Vancomycin Resistance Serine Racemase Vantg


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the Cytoplasmic Domain of Vancomycin Resistance Serine Racemase Vantg within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl402

b:20.5
occ:0.60
 N A:SER203 3.2 15.8 1.0
O A:HOH528 3.2 23.6 1.0
N A:GLY206 3.3 25.5 1.0
O A:HOH584 3.5 30.4 1.0
CB A:ALA164 3.5 26.7 1.0
CB A:SER203 3.6 28.3 1.0
CA A:GLY206 3.6 26.5 1.0
CA A:SER203 3.8 23.9 1.0
O A:HOH518 4.0 26.9 1.0
C A:SER203 4.0 22.3 1.0
CB A:LEU161 4.0 21.6 1.0
CD1 A:LEU161 4.1 23.3 1.0
O A:SER203 4.1 21.4 1.0
OG A:SER203 4.2 41.9 1.0
C A:TYR205 4.2 26.2 1.0
C A:GLN202 4.2 19.1 1.0
CA A:GLN202 4.3 16.5 1.0
CG A:LEU161 4.4 27.8 1.0
N A:TYR205 4.5 22.3 1.0
O A:LEU161 4.6 25.9 1.0
O A:ILE201 4.6 20.9 1.0
CA A:TYR205 4.7 27.9 1.0
N A:SER204 4.7 23.4 1.0
N A:LEU161 4.8 23.6 1.0
CB A:TYR205 4.8 28.0 1.0
CA A:LEU161 4.9 23.3 1.0
CA A:ALA164 4.9 28.5 1.0

Chlorine binding site 3 out of 8 in 4ecl

Go back to Chlorine Binding Sites List in 4ecl
Chlorine binding site 3 out of 8 in the Crystal Structure of the Cytoplasmic Domain of Vancomycin Resistance Serine Racemase Vantg


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of the Cytoplasmic Domain of Vancomycin Resistance Serine Racemase Vantg within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl401

b:33.2
occ:0.79
 NZ B:LYS125 3.0 27.9 0.5
NE2 A:GLN316 3.1 39.2 1.0
N B:LEU133 3.3 27.5 1.0
CE B:MSE130 3.4 21.8 1.0
CE B:LYS125 3.5 33.7 0.5
CB B:ARG132 3.5 39.6 1.0
CB B:LEU133 3.6 26.0 1.0
CE B:LYS125 3.7 32.1 0.5
CG B:LEU133 3.7 27.0 1.0
NZ B:LYS125 3.8 33.7 0.5
CA B:LEU133 3.9 30.7 1.0
CD1 B:LEU133 4.0 29.1 1.0
CD A:GLN316 4.0 35.7 1.0
OE1 A:GLN316 4.1 31.6 1.0
O B:LEU133 4.1 32.2 1.0
CD B:LYS125 4.1 32.5 0.5
C B:ARG132 4.3 29.8 1.0
CD B:LYS125 4.3 32.9 0.5
CD B:ARG132 4.4 42.5 1.0
C B:LEU133 4.4 31.4 1.0
CA B:ARG132 4.5 36.2 1.0
O B:HOH570 4.5 29.3 1.0
CG B:ARG132 4.5 45.5 1.0

Chlorine binding site 4 out of 8 in 4ecl

Go back to Chlorine Binding Sites List in 4ecl
Chlorine binding site 4 out of 8 in the Crystal Structure of the Cytoplasmic Domain of Vancomycin Resistance Serine Racemase Vantg


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of the Cytoplasmic Domain of Vancomycin Resistance Serine Racemase Vantg within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl402

b:13.9
occ:0.45
 O B:HOH538 3.0 27.5 1.0
N B:SER203 3.1 26.7 1.0
N B:GLY206 3.2 27.6 1.0
CA B:GLY206 3.5 26.9 1.0
CB B:ALA164 3.5 33.9 1.0
CB B:SER203 3.5 25.1 1.0
CA B:SER203 3.7 29.9 1.0
CB B:LEU161 3.7 26.4 1.0
CD1 B:LEU161 4.0 30.8 1.0
C B:SER203 4.0 22.3 1.0
O B:HOH615 4.1 28.3 1.0
O B:SER203 4.1 25.1 1.0
C B:GLN202 4.1 24.3 1.0
C B:TYR205 4.2 35.2 1.0
CG B:LEU161 4.2 29.3 1.0
CA B:GLN202 4.2 28.5 1.0
OG B:SER203 4.3 43.1 1.0
N B:TYR205 4.5 27.1 1.0
O B:ILE201 4.6 26.3 1.0
O B:LEU161 4.6 37.7 1.0
CA B:LEU161 4.7 32.2 1.0
CA B:TYR205 4.7 31.1 1.0
N B:LEU161 4.7 27.9 1.0
N B:SER204 4.8 23.6 1.0
CB B:TYR205 4.9 36.4 1.0
CA B:ALA164 4.9 36.9 1.0
O B:TYR205 5.0 33.0 1.0
C B:GLY206 5.0 25.6 1.0

Chlorine binding site 5 out of 8 in 4ecl

Go back to Chlorine Binding Sites List in 4ecl
Chlorine binding site 5 out of 8 in the Crystal Structure of the Cytoplasmic Domain of Vancomycin Resistance Serine Racemase Vantg


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Crystal Structure of the Cytoplasmic Domain of Vancomycin Resistance Serine Racemase Vantg within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl401

b:33.8
occ:0.86
 O C:HOH534 2.9 32.5 1.0
N C:SER203 3.1 23.8 1.0
N C:GLY206 3.2 27.7 1.0
CB C:SER203 3.4 27.8 1.0
CA C:GLY206 3.5 26.0 1.0
CB C:ALA164 3.6 34.6 1.0
CA C:SER203 3.6 25.9 1.0
C C:SER203 3.9 24.1 1.0
CD1 C:LEU161 4.0 32.1 1.0
OG C:SER203 4.0 35.7 1.0
O C:SER203 4.0 30.2 1.0
O C:HOH596 4.1 27.8 1.0
CB C:LEU161 4.1 26.9 1.0
C C:GLN202 4.2 24.0 1.0
C C:TYR205 4.2 31.6 1.0
CA C:GLN202 4.3 27.1 1.0
CG C:LEU161 4.4 29.8 1.0
O C:HOH644 4.4 54.1 1.0
N C:TYR205 4.4 19.5 1.0
CA C:TYR205 4.7 26.7 1.0
O C:ILE201 4.7 31.8 1.0
N C:SER204 4.7 20.5 1.0
CB C:TYR205 4.8 24.3 1.0
O C:LEU161 4.8 36.1 1.0
N C:LEU161 4.9 26.2 1.0
C C:GLY206 5.0 29.3 1.0
CA C:ALA164 5.0 39.3 1.0

Chlorine binding site 6 out of 8 in 4ecl

Go back to Chlorine Binding Sites List in 4ecl
Chlorine binding site 6 out of 8 in the Crystal Structure of the Cytoplasmic Domain of Vancomycin Resistance Serine Racemase Vantg


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Crystal Structure of the Cytoplasmic Domain of Vancomycin Resistance Serine Racemase Vantg within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl401

b:53.9
occ:1.00
 N D:ILE332 3.2 24.9 1.0
O D:HOH516 3.5 24.5 1.0
CA D:SER331 3.7 28.3 1.0
C D:SER331 4.0 31.7 1.0
CB D:ILE332 4.2 29.8 1.0
CB D:SER331 4.2 30.6 1.0
CA D:ILE332 4.3 27.0 1.0
CG1 D:ILE332 4.4 35.9 1.0
OG D:SER331 4.5 34.9 1.0
CD1 D:ILE332 4.6 35.8 1.0
O D:ILE332 4.7 32.0 1.0
O D:GLY330 4.8 32.4 1.0
N D:SER331 4.8 29.7 1.0
C D:ILE332 5.0 28.9 1.0

Chlorine binding site 7 out of 8 in 4ecl

Go back to Chlorine Binding Sites List in 4ecl
Chlorine binding site 7 out of 8 in the Crystal Structure of the Cytoplasmic Domain of Vancomycin Resistance Serine Racemase Vantg


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of Crystal Structure of the Cytoplasmic Domain of Vancomycin Resistance Serine Racemase Vantg within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl402

b:36.4
occ:0.98
 N D:SER203 3.1 14.0 1.0
N D:GLY206 3.1 22.7 1.0
O D:HOH521 3.1 31.2 1.0
O D:HOH607 3.4 31.1 1.0
CB D:SER203 3.4 20.0 1.0
CA D:GLY206 3.5 25.2 1.0
CB D:ALA164 3.6 28.9 1.0
CA D:SER203 3.6 19.4 1.0
O D:HOH559 3.7 24.6 1.0
C D:SER203 3.8 25.5 1.0
O D:SER203 3.9 24.2 1.0
C D:TYR205 4.1 26.5 1.0
CB D:LEU161 4.1 15.0 1.0
OG D:SER203 4.1 28.9 1.0
C D:GLN202 4.1 17.1 1.0
CD1 D:LEU161 4.2 21.7 1.0
CA D:GLN202 4.3 21.5 1.0
N D:TYR205 4.3 13.6 1.0
CA D:TYR205 4.5 22.1 1.0
N D:SER204 4.6 23.8 1.0
CG D:LEU161 4.6 19.4 1.0
CB D:TYR205 4.7 23.3 1.0
O D:LEU161 4.7 20.6 1.0
O D:ILE201 4.8 23.9 1.0
C D:GLY206 4.9 28.4 1.0
CB D:GLN202 4.9 28.1 1.0
CA D:ALA164 5.0 30.4 1.0
O D:TYR205 5.0 24.2 1.0

Chlorine binding site 8 out of 8 in 4ecl

Go back to Chlorine Binding Sites List in 4ecl
Chlorine binding site 8 out of 8 in the Crystal Structure of the Cytoplasmic Domain of Vancomycin Resistance Serine Racemase Vantg


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 8 of Crystal Structure of the Cytoplasmic Domain of Vancomycin Resistance Serine Racemase Vantg within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl403

b:39.5
occ:1.00
 NZ D:LYS125 3.0 37.7 1.0
O D:HOH584 3.3 29.6 1.0
N D:LEU133 3.4 22.0 1.0
NE2 C:GLN316 3.4 23.6 1.0
CB D:ARG132 3.5 15.0 1.0
CE D:LYS125 3.7 37.9 1.0
SE D:MSE130 3.8 49.8 0.8
CB D:LEU133 3.9 26.6 1.0
CG D:MSE130 3.9 36.8 1.0
CA D:LEU133 4.1 26.4 1.0
O D:LEU133 4.1 21.7 1.0
CG D:LEU133 4.2 23.9 1.0
CD1 D:LEU133 4.4 24.3 1.0
CD D:ARG132 4.4 25.2 1.0
CD C:GLN316 4.4 30.9 1.0
C D:ARG132 4.4 23.0 1.0
CA D:ARG132 4.4 20.4 1.0
OE1 C:GLN316 4.5 24.1 1.0
CG D:ARG132 4.5 19.6 1.0
C D:LEU133 4.6 28.1 1.0
CD D:LYS125 4.6 36.4 1.0
CB D:MSE130 4.8 27.6 1.0
N D:ARG132 4.8 21.1 1.0
CB D:HIS160 4.9 32.7 1.0
O D:HOH547 4.9 27.0 1.0
ND1 D:HIS160 5.0 44.9 1.0

Reference:

D.Meziane-Cherif, P.J.Stogios, E.Evdokimova, O.Egorova, A.Savchenko, P.Courvalin. Structural and Functional Adaptation of Vancomycin Resistance Vant Serine Racemases. Mbio V. 6 00806 2015.
ISSN: ESSN 2150-7511
PubMed: 26265719
DOI: 10.1128/MBIO.00806-15
Page generated: Fri Jul 11 14:45:20 2025

Last articles

Mg in 5L5B
Mg in 5L5A
Mg in 5L55
Mg in 5L52
Mg in 5L54
Mg in 5L3S
Mg in 5L44
Mg in 5L3R
Mg in 5L43
Mg in 5L3Q
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy