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Atomistry » Chlorine » PDB 4gta-4h1t » 4h12 » |
Chlorine in PDB 4h12: The Crystal Structure of Methyltransferase Domain of Human Set Domain- Containing Protein 2 in Complex with S-Adenosyl-L-HomocysteineEnzymatic activity of The Crystal Structure of Methyltransferase Domain of Human Set Domain- Containing Protein 2 in Complex with S-Adenosyl-L-Homocysteine
All present enzymatic activity of The Crystal Structure of Methyltransferase Domain of Human Set Domain- Containing Protein 2 in Complex with S-Adenosyl-L-Homocysteine:
2.1.1.43; Protein crystallography data
The structure of The Crystal Structure of Methyltransferase Domain of Human Set Domain- Containing Protein 2 in Complex with S-Adenosyl-L-Homocysteine, PDB code: 4h12
was solved by
M.F.Amaya,
A.Dong,
H.Zeng,
F.Mackenzie,
M.Bunnage,
J.Weigelt,
C.Bountra,
C.H.Arrowsmith,
A.M.Edwards,
J.Min,
H.Wu,
Structural Genomics Consortium(Sgc),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4h12:
The structure of The Crystal Structure of Methyltransferase Domain of Human Set Domain- Containing Protein 2 in Complex with S-Adenosyl-L-Homocysteine also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the The Crystal Structure of Methyltransferase Domain of Human Set Domain- Containing Protein 2 in Complex with S-Adenosyl-L-Homocysteine
(pdb code 4h12). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the The Crystal Structure of Methyltransferase Domain of Human Set Domain- Containing Protein 2 in Complex with S-Adenosyl-L-Homocysteine, PDB code: 4h12: Chlorine binding site 1 out of 1 in 4h12Go back to![]() ![]()
Chlorine binding site 1 out
of 1 in the The Crystal Structure of Methyltransferase Domain of Human Set Domain- Containing Protein 2 in Complex with S-Adenosyl-L-Homocysteine
![]() Mono view ![]() Stereo pair view
Reference:
W.Zheng,
G.Ibanez,
H.Wu,
G.Blum,
H.Zeng,
A.Dong,
F.Li,
T.Hajian,
A.Allali-Hassani,
M.F.Amaya,
A.Siarheyeva,
W.Yu,
P.J.Brown,
M.Schapira,
M.Vedadi,
J.Min,
M.Luo.
Sinefungin Derivatives As Inhibitors and Structure Probes of Protein Lysine Methyltransferase SETD2. J.Am.Chem.Soc. V. 134 18004 2012.
Page generated: Sun Jul 21 15:12:25 2024
ISSN: ISSN 0002-7863 PubMed: 23043551 DOI: 10.1021/JA307060P |
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