Chlorine in PDB 4hod: Crystal Structure of Leut-E290S with Bound Cl

The structure of Crystal Structure of Leut-E290S with Bound Cl, PDB code: 4hod was solved by A.K.Kantcheva, M.Quick, L.Shi, A.M.L.Winther, S.Stolzenberg, H.Weinstein, J.A.Javitch, P.Nissen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.62 / 3.30
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	87.580, 87.480, 80.860, 90.00, 95.00, 90.00
R / Rfree (%)	19 / 25.4

The structure of Crystal Structure of Leut-E290S with Bound Cl also contains other interesting chemical elements:

Sodium

(Na)

2 atoms

The binding sites of Chlorine atom in the Crystal Structure of Leut-E290S with Bound Cl (pdb code 4hod). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Leut-E290S with Bound Cl, PDB code: 4hod:

Chlorine binding site 1 out of 1 in the Crystal Structure of Leut-E290S with Bound Cl


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Leut-E290S with Bound Cl within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl604 b:0.2 occ:1.00 OG A:SER290 2.9 0.0 1.0 OH A:TYR47 2.9 91.3 1.0 OG1 A:THR254 3.0 99.2 1.0 CB A:THR254 3.1 93.4 1.0 NE2 A:GLN250 3.2 0.0 1.0 CG2 A:THR254 3.5 86.9 1.0 CD1 A:PHE31 3.6 0.9 1.0 CE1 A:TYR47 3.6 98.7 1.0 CZ A:TYR47 3.7 99.2 1.0 CG A:GLN250 3.8 0.3 1.0 CB A:SER290 3.9 97.2 1.0 CD A:GLN250 4.0 0.5 1.0 CG A:PHE31 4.0 1.0 1.0 CB A:PHE31 4.0 0.2 1.0 O A:GLN250 4.0 0.6 1.0 CE1 A:PHE31 4.3 0.1 1.0 OE1 A:GLU287 4.5 0.9 1.0 CA A:THR254 4.6 97.0 1.0 OE2 A:GLU287 4.7 0.7 1.0 C A:GLN250 4.9 0.3 1.0 CD1 A:TYR47 4.9 95.7 1.0 CD2 A:PHE31 4.9 0.4 1.0 CE2 A:TYR47 5.0 0.0 1.0 ND2 A:ASN27 5.0 95.4 1.0

A.K.Kantcheva, M.Quick, L.Shi, A.M.L.Winther, S.Stolzenberg, H.Weinstein, J.A.Javitch, P.Nissen. The Chloride Binding Site of Neurotransmitter Sodium Symporters Proc.Natl.Acad.Sci.Usa 2013.
ISSN: ESSN 1091-6490