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Atomistry » Chlorine » PDB 4iik-4io3 » 4iku » |
Chlorine in PDB 4iku: Crystal Structure of Truncated (Delta 1-89) Human Methionine Aminopeptidase Type 1 in Complex with 2-((5-Chloro-6-Methyl-2- (Pyridin-2-Yl)Pyrimidin-4-Yl)Amino)-3-PhenylpropanamideEnzymatic activity of Crystal Structure of Truncated (Delta 1-89) Human Methionine Aminopeptidase Type 1 in Complex with 2-((5-Chloro-6-Methyl-2- (Pyridin-2-Yl)Pyrimidin-4-Yl)Amino)-3-Phenylpropanamide
All present enzymatic activity of Crystal Structure of Truncated (Delta 1-89) Human Methionine Aminopeptidase Type 1 in Complex with 2-((5-Chloro-6-Methyl-2- (Pyridin-2-Yl)Pyrimidin-4-Yl)Amino)-3-Phenylpropanamide:
3.4.11.18; Protein crystallography data
The structure of Crystal Structure of Truncated (Delta 1-89) Human Methionine Aminopeptidase Type 1 in Complex with 2-((5-Chloro-6-Methyl-2- (Pyridin-2-Yl)Pyrimidin-4-Yl)Amino)-3-Phenylpropanamide, PDB code: 4iku
was solved by
A.Addlagatta,
C.Kishor,
T.Arya,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4iku:
The structure of Crystal Structure of Truncated (Delta 1-89) Human Methionine Aminopeptidase Type 1 in Complex with 2-((5-Chloro-6-Methyl-2- (Pyridin-2-Yl)Pyrimidin-4-Yl)Amino)-3-Phenylpropanamide also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Truncated (Delta 1-89) Human Methionine Aminopeptidase Type 1 in Complex with 2-((5-Chloro-6-Methyl-2- (Pyridin-2-Yl)Pyrimidin-4-Yl)Amino)-3-Phenylpropanamide
(pdb code 4iku). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Truncated (Delta 1-89) Human Methionine Aminopeptidase Type 1 in Complex with 2-((5-Chloro-6-Methyl-2- (Pyridin-2-Yl)Pyrimidin-4-Yl)Amino)-3-Phenylpropanamide, PDB code: 4iku: Chlorine binding site 1 out of 1 in 4ikuGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Crystal Structure of Truncated (Delta 1-89) Human Methionine Aminopeptidase Type 1 in Complex with 2-((5-Chloro-6-Methyl-2- (Pyridin-2-Yl)Pyrimidin-4-Yl)Amino)-3-Phenylpropanamide
![]() Mono view ![]() Stereo pair view
Reference:
C.Kishor,
T.Arya,
R.Reddi,
X.Chen,
V.Saddanapu,
A.K.Marapaka,
R.Gumpena,
D.Ma,
J.O.Liu,
A.Addlagatta.
Identification, Biochemical and Structural Evaluation of Species-Specific Inhibitors Against Type I Methionine Aminopeptidases J.Med.Chem. V. 56 5295 2013.
Page generated: Fri Jul 11 16:56:35 2025
ISSN: ISSN 0022-2623 PubMed: 23767698 DOI: 10.1021/JM400395P |
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