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Atomistry » Chlorine » PDB 4ixv-4j8p » 4j51 » |
Chlorine in PDB 4j51: Cyrstal Structure of Protein Tyrosine Phosphatase Lyp Catalytic Domain Complex with Small Molecular Inhibitor L75N04Enzymatic activity of Cyrstal Structure of Protein Tyrosine Phosphatase Lyp Catalytic Domain Complex with Small Molecular Inhibitor L75N04
All present enzymatic activity of Cyrstal Structure of Protein Tyrosine Phosphatase Lyp Catalytic Domain Complex with Small Molecular Inhibitor L75N04:
3.1.3.48; Protein crystallography data
The structure of Cyrstal Structure of Protein Tyrosine Phosphatase Lyp Catalytic Domain Complex with Small Molecular Inhibitor L75N04, PDB code: 4j51
was solved by
D.Liu,
Y.He,
Z.-Y.Zhang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Cyrstal Structure of Protein Tyrosine Phosphatase Lyp Catalytic Domain Complex with Small Molecular Inhibitor L75N04
(pdb code 4j51). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Cyrstal Structure of Protein Tyrosine Phosphatase Lyp Catalytic Domain Complex with Small Molecular Inhibitor L75N04, PDB code: 4j51: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 4j51Go back to![]() ![]()
Chlorine binding site 1 out
of 2 in the Cyrstal Structure of Protein Tyrosine Phosphatase Lyp Catalytic Domain Complex with Small Molecular Inhibitor L75N04
![]() Mono view ![]() Stereo pair view
Chlorine binding site 2 out of 2 in 4j51Go back to![]() ![]()
Chlorine binding site 2 out
of 2 in the Cyrstal Structure of Protein Tyrosine Phosphatase Lyp Catalytic Domain Complex with Small Molecular Inhibitor L75N04
![]() Mono view ![]() Stereo pair view
Reference:
Y.He,
S.Liu,
A.Menon,
S.Stanford,
E.Oppong,
A.M.Gunawan,
L.Wu,
D.J.Wu,
A.M.Barrios,
N.Bottini,
A.C.Cato,
Z.Y.Zhang.
A Potent and Selective Small-Molecule Inhibitor For the Lymphoid-Specific Tyrosine Phosphatase (Lyp), A Target Associated with Autoimmune Diseases. J.Med.Chem. V. 56 4990 2013.
Page generated: Sun Jul 21 17:13:50 2024
ISSN: ISSN 0022-2623 PubMed: 23713581 DOI: 10.1021/JM400248C |
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