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Chlorine in PDB 4lc6: Crystal Structure of the Mutant H128Q of Orotidine 5'-Monophosphate Decarboxylase From Methanobacterium Thermoautotrophicum Complexed with the Inhibitor Bmp

Enzymatic activity of Crystal Structure of the Mutant H128Q of Orotidine 5'-Monophosphate Decarboxylase From Methanobacterium Thermoautotrophicum Complexed with the Inhibitor Bmp

All present enzymatic activity of Crystal Structure of the Mutant H128Q of Orotidine 5'-Monophosphate Decarboxylase From Methanobacterium Thermoautotrophicum Complexed with the Inhibitor Bmp:
4.1.1.23;

Protein crystallography data

The structure of Crystal Structure of the Mutant H128Q of Orotidine 5'-Monophosphate Decarboxylase From Methanobacterium Thermoautotrophicum Complexed with the Inhibitor Bmp, PDB code: 4lc6 was solved by A.A.Fedorov, E.V.Fedorov, B.Desai, J.A.Gerlt, S.C.Almo, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 41.93 / 1.32
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 59.728, 63.790, 61.453, 90.00, 115.13, 90.00
R / Rfree (%) 15 / 16.5

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of the Mutant H128Q of Orotidine 5'-Monophosphate Decarboxylase From Methanobacterium Thermoautotrophicum Complexed with the Inhibitor Bmp (pdb code 4lc6). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the Mutant H128Q of Orotidine 5'-Monophosphate Decarboxylase From Methanobacterium Thermoautotrophicum Complexed with the Inhibitor Bmp, PDB code: 4lc6:

Chlorine binding site 1 out of 1 in 4lc6

Go back to Chlorine Binding Sites List in 4lc6
Chlorine binding site 1 out of 1 in the Crystal Structure of the Mutant H128Q of Orotidine 5'-Monophosphate Decarboxylase From Methanobacterium Thermoautotrophicum Complexed with the Inhibitor Bmp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Mutant H128Q of Orotidine 5'-Monophosphate Decarboxylase From Methanobacterium Thermoautotrophicum Complexed with the Inhibitor Bmp within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl302

b:38.7
occ:1.00
N A:GLU162 3.3 13.2 1.0
CB A:GLU162 3.4 15.2 1.0
CA A:ARG160 3.5 10.4 1.0
C A:ARG160 3.5 11.1 1.0
CB A:ARG160 3.5 13.9 1.0
N A:PRO161 3.7 12.3 1.0
CG A:GLU162 3.8 21.9 1.0
CA A:GLU162 3.9 13.0 1.0
O A:ARG160 3.9 10.4 1.0
N A:ARG163 3.9 9.4 1.0
CD A:PRO161 4.1 13.7 1.0
CG A:ARG160 4.1 19.8 1.0
C A:PRO161 4.3 12.8 1.0
CG A:ARG163 4.4 13.5 1.0
C A:GLU162 4.4 11.8 1.0
CA A:PRO161 4.6 12.2 1.0
CD A:ARG160 4.6 21.7 1.0
N A:ARG160 4.9 9.3 1.0
CB A:ARG163 4.9 10.6 1.0

Reference:

A.A.Fedorov, E.V.Fedorov, B.Desai, J.A.Gerlt, S.C.Almo. Crystal Structure of the Mutant H128Q of Orotidine 5'-Monophosphate Decarboxylase From Methanobacterium Thermoautotrophicum Complexed with the Inhibitor Bmp To Be Published.
Page generated: Fri Jul 11 18:30:51 2025

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