Chlorine in PDB 4lgp: Ricin A Chain Bound to Camelid Nanobody (VHH1)

All present enzymatic activity of Ricin A Chain Bound to Camelid Nanobody (VHH1):
3.2.2.22;

The structure of Ricin A Chain Bound to Camelid Nanobody (VHH1), PDB code: 4lgp was solved by M.J.Rudolph, J.Cheung, M.Franklin, F.Burshteyn, M.Cassidy, E.Gary, N.Mantis, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.22 / 2.40
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	90.168, 92.443, 93.317, 90.00, 90.00, 90.00
R / Rfree (%)	22.5 / 28.1

The binding sites of Chlorine atom in the Ricin A Chain Bound to Camelid Nanobody (VHH1) (pdb code 4lgp). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Ricin A Chain Bound to Camelid Nanobody (VHH1), PDB code: 4lgp:

Chlorine binding site 1 out of 1 in the Ricin A Chain Bound to Camelid Nanobody (VHH1)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Ricin A Chain Bound to Camelid Nanobody (VHH1) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl301 b:74.7 occ:1.00 O A:HOH418 2.1 52.5 1.0 OD1 A:ASN122 3.4 38.4 1.0 N A:GLY120 3.4 29.7 1.0 CA A:GLY120 3.8 29.2 1.0 O A:HOH443 4.0 42.8 1.0 NH2 B:ARG52 4.1 52.3 1.0 NH1 A:ARG125 4.2 45.5 1.0 CG A:ARG125 4.2 36.9 1.0 CB A:ARG125 4.2 38.1 1.0 CZ A:ARG125 4.4 49.0 1.0 CG A:ASN122 4.4 38.2 1.0 C A:PHE119 4.6 30.5 1.0 ND2 A:ASN122 4.6 41.1 1.0 C A:GLY120 4.6 28.5 1.0 NE A:ARG125 4.7 38.4 1.0 NH2 A:ARG125 4.8 51.7 1.0 CA A:PHE119 4.8 31.5 1.0

M.J.Rudolph, D.J.Vance, J.Cheung, M.C.Franklin, F.Burshteyn, M.S.Cassidy, E.N.Gary, C.Herrera, C.B.Shoemaker, N.J.Mantis. Crystal Structures of Ricin Toxin'S Enzymatic Subunit (Rta) in Complex with Neutralizing and Non-Neutralizing Single-Chain Antibodies. J.Mol.Biol. V. 426 3057 2014.
ISSN: ISSN 0022-2836
PubMed: 24907552
DOI: 10.1016/J.JMB.2014.05.026