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Atomistry » Chlorine » PDB 4lr4-4lxd » 4lxb | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 4lr4-4lxd » 4lxb » |
Chlorine in PDB 4lxb: Crystal Structure Analysis of Thrombin in Complex with Compound D58Enzymatic activity of Crystal Structure Analysis of Thrombin in Complex with Compound D58
All present enzymatic activity of Crystal Structure Analysis of Thrombin in Complex with Compound D58:
3.4.21.5; Protein crystallography data
The structure of Crystal Structure Analysis of Thrombin in Complex with Compound D58, PDB code: 4lxb
was solved by
C.Stehlin-Gaon,
Z.Bocskei,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4lxb:
The structure of Crystal Structure Analysis of Thrombin in Complex with Compound D58 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure Analysis of Thrombin in Complex with Compound D58
(pdb code 4lxb). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure Analysis of Thrombin in Complex with Compound D58, PDB code: 4lxb: Chlorine binding site 1 out of 1 in 4lxbGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Crystal Structure Analysis of Thrombin in Complex with Compound D58
![]() Mono view ![]() Stereo pair view
Reference:
J.Meneyrol,
M.Follmann,
G.Lassalle,
V.Wehner,
G.Barre,
T.Rousseaux,
J.M.Altenburger,
F.Petit,
Z.Bocskei,
H.Schreuder,
N.Alet,
J.P.Herault,
L.Millet,
F.Dol,
P.Florian,
P.Schaeffer,
F.Sadoun,
S.Klieber,
C.Briot,
F.Bono,
J.M.Herbert.
5-Chlorothiophene-2-Carboxylic Acid [(S)-2-[2-Methyl-3-(2-Oxopyrrolidin-1-Yl) Benzenesulfonylamino]-3-(4-Methylpiperazin-1-Yl)-3- Oxopropyl]Amide (SAR107375), A Selective and Potent Orally Active Dual Thrombin and Factor Xa Inhibitor. J.Med.Chem. V. 56 9441 2013.
Page generated: Sun Jul 21 19:21:26 2024
ISSN: ISSN 0022-2623 PubMed: 24175584 DOI: 10.1021/JM4005835 |
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