Chlorine in PDB 4lzd: Human Dna Polymerase Mu- Apoenzyme

All present enzymatic activity of Human Dna Polymerase Mu- Apoenzyme:
2.7.7.7;

The structure of Human Dna Polymerase Mu- Apoenzyme, PDB code: 4lzd was solved by A.F.Moon, J.M.Pryor, D.A.Ramsden, T.A.Kunkel, K.Bebenek, L.C.Pedersen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	25.86 / 1.85
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	124.192, 124.192, 50.407, 90.00, 90.00, 90.00
R / Rfree (%)	18.1 / 22.8

The structure of Human Dna Polymerase Mu- Apoenzyme also contains other interesting chemical elements:

Sodium

(Na)

1 atom

The binding sites of Chlorine atom in the Human Dna Polymerase Mu- Apoenzyme (pdb code 4lzd). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human Dna Polymerase Mu- Apoenzyme, PDB code: 4lzd:

Chlorine binding site 1 out of 1 in the Human Dna Polymerase Mu- Apoenzyme


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Dna Polymerase Mu- Apoenzyme within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl504 b:47.7 occ:1.00 O A:HOH928 2.6 32.7 0.5 O A:HOH910 3.0 29.0 1.0 O A:HOH909 3.1 36.4 1.0 N A:LYS438 3.2 13.5 1.0 O A:HOH928 3.2 27.9 0.2 O A:HOH928 3.2 30.7 0.2 O A:HOH674 3.7 18.8 1.0 CB A:SER437 3.8 15.2 1.0 CB A:LYS438 3.8 21.7 1.0 CA A:SER437 3.9 13.7 1.0 C A:SER437 4.0 11.3 1.0 CA A:LYS438 4.1 17.8 1.0 NH1 A:ARG323 4.1 26.2 1.0 NH2 A:ARG323 4.6 17.8 1.0 CZ A:ARG323 4.7 18.8 1.0 OG A:SER437 4.9 13.6 1.0 O A:HOH817 5.0 27.4 1.0

A.F.Moon, J.M.Pryor, D.A.Ramsden, T.A.Kunkel, K.Bebenek, L.C.Pedersen. Sustained Active Site Rigidity During Synthesis By Human Dna Polymerase Mu. Nat.Struct.Mol.Biol. V. 21 253 2014.
ISSN: ISSN 1545-9993
PubMed: 24487959
DOI: 10.1038/NSMB.2766