Chlorine in PDB 4m69: Crystal Structure of the Mouse RIP3-Mlkl Complex

All present enzymatic activity of Crystal Structure of the Mouse RIP3-Mlkl Complex:
2.7.11.1;

The structure of Crystal Structure of the Mouse RIP3-Mlkl Complex, PDB code: 4m69 was solved by T.Xie, W.Peng, C.Yan, J.Wu, Y.Shi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.57 / 2.50
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	106.443, 141.951, 107.129, 90.00, 90.00, 90.00
R / Rfree (%)	22 / 24.6

The structure of Crystal Structure of the Mouse RIP3-Mlkl Complex also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Chlorine atom in the Crystal Structure of the Mouse RIP3-Mlkl Complex (pdb code 4m69). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of the Mouse RIP3-Mlkl Complex, PDB code: 4m69:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of the Mouse RIP3-Mlkl Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Mouse RIP3-Mlkl Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl404 b:75.1 occ:1.00 N A:ASP86 3.3 42.8 1.0 O A:HOH573 3.4 57.4 1.0 OD1 A:ASP86 3.6 43.7 1.0 O A:GLN84 3.9 56.1 1.0 CA A:TRP85 3.9 36.0 1.0 CE A:LYS24 3.9 49.0 1.0 C A:TRP85 4.1 36.3 1.0 CA A:ASP86 4.3 43.1 1.0 CD A:LYS24 4.6 48.7 1.0 CG A:ASP86 4.7 43.7 1.0 C A:GLN84 4.7 56.0 1.0 N A:TRP85 4.8 35.8 1.0 CB A:TRP85 4.8 36.1 1.0 CD1 A:TRP85 4.9 36.1 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of the Mouse RIP3-Mlkl Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the Mouse RIP3-Mlkl Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl405 b:81.8 occ:1.00 NH1 A:ARG42 3.1 44.0 1.0 CE A:LYS23 3.9 50.5 1.0 CD A:LYS23 4.1 50.6 1.0 CZ A:ARG42 4.3 43.5 1.0 NZ A:LYS23 4.3 51.1 1.0 NH2 A:ARG42 4.7 42.9 1.0 CG A:LYS23 4.7 49.9 1.0

T.Xie, W.Peng, C.Yan, J.Wu, X.Gong, Y.Shi. Structural Insights Into RIP3-Mediated Necroptotic Signaling Cell Rep V. 5 70 2013.
ISSN: ESSN 2211-1247
PubMed: 24095729
DOI: 10.1016/J.CELREP.2013.08.044