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Atomistry » Chlorine » PDB 4mlb-4ms4 » 4mrw | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 4mlb-4ms4 » 4mrw » |
Chlorine in PDB 4mrw: Crystal Structure of PDE10A2 with Fragment ZT0120 (7-Chloroquinolin-4- Ol)Enzymatic activity of Crystal Structure of PDE10A2 with Fragment ZT0120 (7-Chloroquinolin-4- Ol)
All present enzymatic activity of Crystal Structure of PDE10A2 with Fragment ZT0120 (7-Chloroquinolin-4- Ol):
3.1.4.17; 3.1.4.35; Protein crystallography data
The structure of Crystal Structure of PDE10A2 with Fragment ZT0120 (7-Chloroquinolin-4- Ol), PDB code: 4mrw
was solved by
V.Sridhar,
J.Badger,
C.Logan,
B Chie-Leon,
V.Nienaber,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4mrw:
The structure of Crystal Structure of PDE10A2 with Fragment ZT0120 (7-Chloroquinolin-4- Ol) also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of PDE10A2 with Fragment ZT0120 (7-Chloroquinolin-4- Ol)
(pdb code 4mrw). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of PDE10A2 with Fragment ZT0120 (7-Chloroquinolin-4- Ol), PDB code: 4mrw: Chlorine binding site 1 out of 1 in 4mrwGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Crystal Structure of PDE10A2 with Fragment ZT0120 (7-Chloroquinolin-4- Ol)
![]() Mono view ![]() Stereo pair view
Reference:
M.I.Recht,
V.Sridhar,
J.Badger,
P.Y.Bounaud,
C.Logan,
B.Chie-Leon,
V.Nienaber,
F.E.Torres.
Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening By Nanocalorimetry and X-Ray Crystallography. J Biomol Screen V. 19 497 2014.
Page generated: Sun Jul 21 20:09:53 2024
ISSN: ISSN 1087-0571 PubMed: 24375910 DOI: 10.1177/1087057113516493 |
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