Chlorine in PDB 4ntw: Structure of Acid-Sensing Ion Channel in Complex with Snake Toxin

The structure of Structure of Acid-Sensing Ion Channel in Complex with Snake Toxin, PDB code: 4ntw was solved by I.Baconguis, C.J.Bohlen, A.Goehring, D.Julius, E.Gouaux, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.00 / 2.07
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	151.930, 151.930, 123.790, 90.00, 90.00, 120.00
R / Rfree (%)	20.6 / 24.6

The structure of Structure of Acid-Sensing Ion Channel in Complex with Snake Toxin also contains other interesting chemical elements:

Sodium

(Na)

3 atoms

The binding sites of Chlorine atom in the Structure of Acid-Sensing Ion Channel in Complex with Snake Toxin (pdb code 4ntw). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of Acid-Sensing Ion Channel in Complex with Snake Toxin, PDB code: 4ntw:

Chlorine binding site 1 out of 1 in the Structure of Acid-Sensing Ion Channel in Complex with Snake Toxin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Acid-Sensing Ion Channel in Complex with Snake Toxin within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl503 b:54.4 occ:1.00 OE2 A:GLU314 3.2 43.8 1.0 NE A:ARG310 3.3 35.5 1.0 NH1 A:ARG310 3.3 36.2 1.0 CG A:GLU314 3.7 31.9 1.0 CZ A:ARG310 3.8 40.5 1.0 CD A:GLU314 3.9 39.7 1.0 CG2 A:VAL353 4.1 40.2 1.0 CB A:ARG310 4.3 33.3 1.0 CG A:LEU352 4.3 41.1 1.0 CD2 A:LEU352 4.4 36.0 1.0 CD A:ARG310 4.5 36.1 1.0 CG A:ARG310 4.5 37.1 1.0 O A:LEU352 4.6 45.3 1.0 CA A:VAL353 4.6 41.3 1.0 O A:ARG310 4.7 32.0 1.0 C A:LEU352 4.8 40.0 1.0 CA A:ARG310 4.8 35.9 1.0 N A:VAL353 4.9 39.5 1.0 CB A:VAL353 4.9 41.5 1.0

I.Baconguis, C.J.Bohlen, A.Goehring, D.Julius, E.Gouaux. X-Ray Structure of Acid-Sensing Ion Channel 1-Snake Toxin Complex Reveals Open State of A Na(+)-Selective Channel. Cell(Cambridge,Mass.) V. 156 717 2014.
ISSN: ISSN 0092-8674
PubMed: 24507937
DOI: 10.1016/J.CELL.2014.01.011