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Atomistry » Chlorine » PDB 4o0c-4oae » 4o6e » |
Chlorine in PDB 4o6e: Discovery of 5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidine Inhibitors of ERK2Enzymatic activity of Discovery of 5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidine Inhibitors of ERK2
All present enzymatic activity of Discovery of 5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidine Inhibitors of ERK2:
2.7.11.24; Protein crystallography data
The structure of Discovery of 5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidine Inhibitors of ERK2, PDB code: 4o6e
was solved by
J.Yin,
W.Wang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4o6e:
The structure of Discovery of 5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidine Inhibitors of ERK2 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Discovery of 5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidine Inhibitors of ERK2
(pdb code 4o6e). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Discovery of 5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidine Inhibitors of ERK2, PDB code: 4o6e: Chlorine binding site 1 out of 1 in 4o6eGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Discovery of 5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidine Inhibitors of ERK2
![]() Mono view ![]() Stereo pair view
Reference:
J.F.Blake,
J.J.Gaudino,
J.De Meese,
P.Mohr,
M.Chicarelli,
H.Tian,
R.Garrey,
A.Thomas,
C.S.Siedem,
M.B.Welch,
G.Kolakowski,
R.Kaus,
M.Burkard,
M.Martinson,
H.Chen,
B.Dean,
D.A.Dudley,
S.E.Gould,
P.Pacheco,
S.Shahidi-Latham,
W.Wang,
K.West,
J.Yin,
J.Moffat,
J.B.Schwarz.
Discovery of 5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidine Inhibitors of ERK2. Bioorg.Med.Chem.Lett. V. 24 2635 2014.
Page generated: Thu Jul 25 23:14:02 2024
ISSN: ISSN 0960-894X PubMed: 24813737 DOI: 10.1016/J.BMCL.2014.04.068 |
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