Chlorine in PDB 4re1: Crystal Structure of Human TEAD1 and Disulfide-Engineered Yap

The structure of Crystal Structure of Human TEAD1 and Disulfide-Engineered Yap, PDB code: 4re1 was solved by Z.Xu, Z.Zhou, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	26.57 / 2.20
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	44.250, 105.030, 164.780, 90.00, 90.00, 90.00
R / Rfree (%)	21.2 / 24.8

The binding sites of Chlorine atom in the Crystal Structure of Human TEAD1 and Disulfide-Engineered Yap (pdb code 4re1). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human TEAD1 and Disulfide-Engineered Yap, PDB code: 4re1:

Chlorine binding site 1 out of 1 in the Crystal Structure of Human TEAD1 and Disulfide-Engineered Yap


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human TEAD1 and Disulfide-Engineered Yap within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl501 b:75.0 occ:1.00 ND1 A:HIS226 3.0 52.9 1.0 N A:HIS229 3.2 72.1 1.0 N A:GLY228 3.2 50.3 1.0 O A:HIS226 3.3 44.3 1.0 CE1 A:HIS226 3.6 52.0 1.0 C A:ILE227 3.7 46.6 1.0 CA A:ILE227 3.7 34.6 1.0 C A:HIS226 3.8 41.7 1.0 C A:HIS229 3.9 74.6 1.0 NE2 A:HIS403 4.0 41.3 1.0 CA A:HIS229 4.0 70.4 1.0 C A:GLY228 4.0 63.5 1.0 N A:ILE227 4.1 38.7 1.0 CA A:GLY228 4.1 53.8 1.0 CG A:HIS226 4.2 45.9 1.0 CD2 A:HIS229 4.3 74.5 1.0 CD2 A:HIS403 4.4 41.4 1.0 O A:ILE227 4.6 41.2 1.0 CB A:HIS226 4.7 42.5 1.0 O A:HIS229 4.7 78.8 1.0 CB A:HIS229 4.7 82.4 1.0 CG A:HIS229 4.7 73.0 1.0 CA A:HIS226 4.9 40.8 1.0 NE2 A:HIS226 4.9 50.5 1.0

Z.Zhou, T.Hu, Z.Xu, Z.Lin, Z.Zhang, T.Feng, L.Zhu, Y.Rong, H.Shen, J.M.Luk, X.Zhang, N.Qin. Targeting Hippo Pathway By Specific Interruption of Yap-Tead Interaction Using Cyclic Yap-Like Peptides Faseb J. 2014.
ISSN: ESSN 1530-6860
DOI: 10.1096/FJ.14-262980