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Chlorine in PDB 4rv8: Co-Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase From Cryptosporidium Parvum and the Inhibitor P131
Enzymatic activity of Co-Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase From Cryptosporidium Parvum and the Inhibitor P131
All present enzymatic activity of Co-Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase From Cryptosporidium Parvum and the Inhibitor P131:
1.1.1.205;
1.1.1.205;
Protein crystallography data
The structure of Co-Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase From Cryptosporidium Parvum and the Inhibitor P131, PDB code: 4rv8
was solved by
Y.Kim,
M.Makowska-Grzyska,
M.Gu,
M.Kavitha,
L.Hedstrom,
W.F.Andesrson,
A.Joachimiak,
Center For Structural Genomics Of Infectious Diseases(Csgid),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 40.84 / 2.05 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 89.188, 91.832, 92.021, 90.00, 103.75, 90.00 |
| R / Rfree (%) | 18.7 / 22.9 |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Co-Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase From Cryptosporidium Parvum and the Inhibitor P131
(pdb code 4rv8). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Co-Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase From Cryptosporidium Parvum and the Inhibitor P131, PDB code: 4rv8:
Jump to Chlorine binding site number: 1; 2; 3; 4;
In total 4 binding sites of Chlorine where determined in the Co-Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase From Cryptosporidium Parvum and the Inhibitor P131, PDB code: 4rv8:
Jump to Chlorine binding site number: 1; 2; 3; 4;
Chlorine binding site 1 out of 4 in 4rv8
Go back to
Chlorine Binding Sites List in 4rv8
Chlorine binding site 1 out
of 4 in the Co-Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase From Cryptosporidium Parvum and the Inhibitor P131
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Co-Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase From Cryptosporidium Parvum and the Inhibitor P131 within 5.0Å range:
|
Chlorine binding site 2 out of 4 in 4rv8
Go back to
Chlorine Binding Sites List in 4rv8
Chlorine binding site 2 out
of 4 in the Co-Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase From Cryptosporidium Parvum and the Inhibitor P131
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 2 of Co-Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase From Cryptosporidium Parvum and the Inhibitor P131 within 5.0Å range:
|
Chlorine binding site 3 out of 4 in 4rv8
Go back to
Chlorine Binding Sites List in 4rv8
Chlorine binding site 3 out
of 4 in the Co-Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase From Cryptosporidium Parvum and the Inhibitor P131
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 3 of Co-Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase From Cryptosporidium Parvum and the Inhibitor P131 within 5.0Å range:
|
Chlorine binding site 4 out of 4 in 4rv8
Go back to
Chlorine Binding Sites List in 4rv8
Chlorine binding site 4 out
of 4 in the Co-Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase From Cryptosporidium Parvum and the Inhibitor P131
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 4 of Co-Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase From Cryptosporidium Parvum and the Inhibitor P131 within 5.0Å range:
|
Reference:
Y.Kim,
M.Makowska-Grzyska,
M.Gu,
M.Kavitha,
L.Hedstrom,
W.F.Andesrson,
A.Joachimiak.
Co-Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase From Cryptosporidium Parvum and the Inhibitor P131 To Be Published.
Page generated: Fri Jul 11 21:35:21 2025
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