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Atomistry » Chlorine » PDB 4u3b-4ufx » 4u6r | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 4u3b-4ufx » 4u6r » |
Chlorine in PDB 4u6r: Crystal Structure of Human IRE1 Cytoplasmic Domains in Complex with A Sulfonamide Inhibitor.Enzymatic activity of Crystal Structure of Human IRE1 Cytoplasmic Domains in Complex with A Sulfonamide Inhibitor.
All present enzymatic activity of Crystal Structure of Human IRE1 Cytoplasmic Domains in Complex with A Sulfonamide Inhibitor.:
2.7.11.1; Protein crystallography data
The structure of Crystal Structure of Human IRE1 Cytoplasmic Domains in Complex with A Sulfonamide Inhibitor., PDB code: 4u6r
was solved by
C.Mohr,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Human IRE1 Cytoplasmic Domains in Complex with A Sulfonamide Inhibitor.
(pdb code 4u6r). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human IRE1 Cytoplasmic Domains in Complex with A Sulfonamide Inhibitor., PDB code: 4u6r: Chlorine binding site 1 out of 1 in 4u6rGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Crystal Structure of Human IRE1 Cytoplasmic Domains in Complex with A Sulfonamide Inhibitor.
![]() Mono view ![]() Stereo pair view
Reference:
P.E.Harrington,
K.Biswas,
D.Malwitz,
A.S.Tasker,
C.Mohr,
K.L.Andrews,
K.Dellamaggiore,
R.Kendall,
H.Beckmann,
P.Jaeckel,
S.Materna-Reichelt,
J.R.Allen,
J.R.Lipford.
Unfolded Protein Response in Cancer: IRE1 Alpha Inhibition By Selective Kinase Ligands Does Not Impair Tumor Cell Viability Acs Med.Chem.Lett. 2014.
Page generated: Fri Jul 26 02:07:29 2024
ISSN: ISSN 1948-5875 DOI: 10.1021/ML500315B |
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