Atomistry » Chlorine » PDB 4uvr-4v3k » 4v07
Atomistry »
  Chlorine »
    PDB 4uvr-4v3k »
      4v07 »

Chlorine in PDB 4v07: Dimeric Pseudorabies Virus Protease PUL26N at 2.1 A Resolution

Enzymatic activity of Dimeric Pseudorabies Virus Protease PUL26N at 2.1 A Resolution

All present enzymatic activity of Dimeric Pseudorabies Virus Protease PUL26N at 2.1 A Resolution:
3.4.21.97;

Protein crystallography data

The structure of Dimeric Pseudorabies Virus Protease PUL26N at 2.1 A Resolution, PDB code: 4v07 was solved by M.Zuehlsdorf, S.Werten, G.J.Palm, W.Hinrichs, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 62.66 / 2.10
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 51.375, 75.986, 110.758, 90.00, 90.00, 90.00
R / Rfree (%) 17.788 / 23.732

Other elements in 4v07:

The structure of Dimeric Pseudorabies Virus Protease PUL26N at 2.1 A Resolution also contains other interesting chemical elements:

Magnesium (Mg) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Dimeric Pseudorabies Virus Protease PUL26N at 2.1 A Resolution (pdb code 4v07). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 7 binding sites of Chlorine where determined in the Dimeric Pseudorabies Virus Protease PUL26N at 2.1 A Resolution, PDB code: 4v07:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7;

Chlorine binding site 1 out of 7 in 4v07

Go back to Chlorine Binding Sites List in 4v07
Chlorine binding site 1 out of 7 in the Dimeric Pseudorabies Virus Protease PUL26N at 2.1 A Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Dimeric Pseudorabies Virus Protease PUL26N at 2.1 A Resolution within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1219

b:46.8
occ:1.00
O A:HOH2040 3.0 45.9 1.0
N A:ARG161 3.4 39.6 1.0
CB A:ARG161 3.5 45.5 1.0
N A:ALA160 3.7 39.0 1.0
CB A:SER159 3.9 39.4 1.0
CA A:ARG161 4.1 42.7 1.0
CB A:ALA160 4.1 40.2 1.0
CA A:ALA160 4.3 39.1 1.0
C A:ALA160 4.3 40.3 1.0
OG A:SER159 4.4 41.1 1.0
C A:SER159 4.4 38.2 1.0
CA A:SER159 4.6 39.4 1.0
CG A:ARG161 4.7 50.8 1.0
CD A:ARG161 4.9 56.5 1.0

Chlorine binding site 2 out of 7 in 4v07

Go back to Chlorine Binding Sites List in 4v07
Chlorine binding site 2 out of 7 in the Dimeric Pseudorabies Virus Protease PUL26N at 2.1 A Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Dimeric Pseudorabies Virus Protease PUL26N at 2.1 A Resolution within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1220

b:42.7
occ:1.00
O A:HOH2059 2.9 55.5 1.0
O B:HOH2063 3.1 35.4 1.0
N A:TRP205 3.2 36.4 1.0
N B:ASP203 3.3 43.0 1.0
N A:ARG204 3.5 38.5 1.0
C A:ASP203 3.6 41.6 1.0
CA A:ASP203 3.7 43.2 1.0
CB A:TRP205 3.9 36.6 1.0
O A:HOH2051 3.9 36.7 1.0
CA B:ARG202 3.9 45.5 1.0
CD1 A:TRP205 3.9 36.7 1.0
CA A:TRP205 4.0 37.1 1.0
CG A:ARG204 4.1 36.8 1.0
C B:ARG202 4.1 43.7 1.0
CA B:ASP203 4.2 42.6 1.0
C A:ARG204 4.2 37.6 1.0
CG A:TRP205 4.3 35.7 1.0
CA A:ARG204 4.3 38.8 1.0
N A:ASP203 4.3 42.4 1.0
CG B:ARG202 4.3 53.9 1.0
OD1 B:ASP203 4.3 54.5 1.0
O A:ASP203 4.3 38.9 1.0
N A:GLU206 4.4 45.0 1.0
O A:HOH2053 4.4 52.3 1.0
O B:LEU201 4.4 40.2 1.0
CB B:ARG202 4.4 48.7 1.0
CL B:CL1225 4.6 39.8 1.0
C A:TRP205 4.7 40.9 1.0
CB A:ARG204 4.8 36.6 1.0
CG B:ASP203 4.8 49.0 1.0
CB A:ASP203 4.9 46.7 1.0

Chlorine binding site 3 out of 7 in 4v07

Go back to Chlorine Binding Sites List in 4v07
Chlorine binding site 3 out of 7 in the Dimeric Pseudorabies Virus Protease PUL26N at 2.1 A Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Dimeric Pseudorabies Virus Protease PUL26N at 2.1 A Resolution within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1221

b:59.0
occ:1.00
OG A:SER109 2.9 49.0 1.0
O A:HOH2029 2.9 42.9 1.0
N A:ARG136 3.3 51.8 1.0
CB A:ARG136 3.6 59.2 1.0
CB A:SER109 3.6 41.5 1.0
CA A:ARG136 3.9 54.6 1.0
CG A:ARG136 4.0 60.3 1.0
CD A:ARG136 4.1 64.6 1.0
C A:GLY135 4.2 54.7 1.0
N A:ARG137 4.2 55.4 1.0
CA A:SER109 4.2 40.8 1.0
CA A:GLY135 4.2 53.5 1.0
O A:HOH2004 4.5 40.9 1.0
C A:ARG136 4.5 56.5 1.0
CG A:ARG137 4.6 59.1 1.0
NH1 A:ARG137 4.8 58.0 1.0

Chlorine binding site 4 out of 7 in 4v07

Go back to Chlorine Binding Sites List in 4v07
Chlorine binding site 4 out of 7 in the Dimeric Pseudorabies Virus Protease PUL26N at 2.1 A Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Dimeric Pseudorabies Virus Protease PUL26N at 2.1 A Resolution within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1222

b:65.1
occ:1.00
CD A:ARG169 3.4 61.9 1.0
N A:VAL55 3.6 38.5 1.0
CA A:ALA54 3.7 39.3 1.0
CD A:PRO33 3.7 66.5 1.0
O A:VAL55 3.8 48.1 1.0
CB A:PRO32 4.0 66.1 1.0
CG A:ARG169 4.1 57.7 1.0
C A:ALA54 4.2 37.3 1.0
CB A:ALA54 4.2 42.1 1.0
NE A:ARG169 4.5 59.1 1.0
O A:LEU53 4.6 43.3 1.0
CA A:PRO32 4.6 67.7 1.0
CG A:PRO33 4.6 62.8 1.0
CA A:VAL55 4.6 40.1 1.0
C A:VAL55 4.6 43.2 1.0
N A:ALA54 4.8 39.3 1.0
N A:PRO33 4.8 66.7 1.0
CB A:VAL55 4.9 43.2 1.0

Chlorine binding site 5 out of 7 in 4v07

Go back to Chlorine Binding Sites List in 4v07
Chlorine binding site 5 out of 7 in the Dimeric Pseudorabies Virus Protease PUL26N at 2.1 A Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Dimeric Pseudorabies Virus Protease PUL26N at 2.1 A Resolution within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl1225

b:39.8
occ:1.00
O A:HOH2054 3.0 58.3 1.0
N A:ASP203 3.1 42.4 1.0
O A:HOH2051 3.2 36.7 1.0
N B:TRP205 3.3 37.3 1.0
N B:ARG204 3.5 38.0 1.0
C B:ASP203 3.7 39.1 1.0
CA B:ASP203 3.7 42.6 1.0
CA A:ARG202 3.8 42.4 1.0
CB B:TRP205 3.8 40.3 1.0
CD1 B:TRP205 3.9 38.9 1.0
C A:ARG202 3.9 41.5 1.0
O B:HOH2063 4.0 35.4 1.0
CA A:ASP203 4.1 43.2 1.0
CA B:TRP205 4.1 39.5 1.0
CG A:ARG202 4.1 49.8 1.0
CG B:TRP205 4.2 39.2 1.0
C B:ARG204 4.3 37.0 1.0
CG B:ARG204 4.3 40.2 1.0
CA B:ARG204 4.3 37.0 1.0
CB A:ARG202 4.3 45.0 1.0
N B:ASP203 4.4 43.0 1.0
N B:GLU206 4.4 41.3 1.0
O B:ASP203 4.4 37.5 1.0
O A:LEU201 4.5 41.1 1.0
O A:HOH2055 4.5 56.7 1.0
OD1 A:ASP203 4.6 52.4 1.0
CL A:CL1220 4.6 42.7 1.0
C B:TRP205 4.8 41.7 1.0
CB B:ARG204 4.8 36.7 1.0
CD A:ARG202 4.8 54.6 1.0
CB B:ASP203 4.9 44.9 1.0
CG A:ASP203 4.9 49.8 1.0
N A:ARG202 5.0 40.4 1.0

Chlorine binding site 6 out of 7 in 4v07

Go back to Chlorine Binding Sites List in 4v07
Chlorine binding site 6 out of 7 in the Dimeric Pseudorabies Virus Protease PUL26N at 2.1 A Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Dimeric Pseudorabies Virus Protease PUL26N at 2.1 A Resolution within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl1226

b:50.0
occ:1.00
N B:ARG136 2.8 41.6 1.0
O B:HOH2040 3.0 38.4 1.0
OG B:SER109 3.1 41.9 1.0
CB B:ARG136 3.4 42.4 1.0
CB B:SER109 3.5 35.5 1.0
CA B:ARG136 3.6 44.6 1.0
C B:GLY135 3.7 45.4 1.0
CA B:GLY135 3.8 40.9 1.0
N B:ARG137 4.0 45.8 1.0
CA B:SER109 4.2 35.5 1.0
O B:HOH2004 4.3 28.9 1.0
C B:ARG136 4.3 50.2 1.0
CG B:ARG137 4.7 42.1 1.0
O B:GLY135 4.9 52.8 1.0

Chlorine binding site 7 out of 7 in 4v07

Go back to Chlorine Binding Sites List in 4v07
Chlorine binding site 7 out of 7 in the Dimeric Pseudorabies Virus Protease PUL26N at 2.1 A Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of Dimeric Pseudorabies Virus Protease PUL26N at 2.1 A Resolution within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl1227

b:58.7
occ:1.00
N B:VAL55 3.1 41.3 1.0
NH1 B:ARG169 3.3 82.1 1.0
CA B:ALA54 3.5 38.8 1.0
CD B:PRO33 3.6 60.6 1.0
C B:ALA54 3.8 40.6 1.0
O B:VAL55 3.9 49.3 1.0
CA B:VAL55 4.2 42.8 1.0
CB B:ALA54 4.3 43.1 1.0
CG B:PRO33 4.4 59.6 1.0
CZ B:ARG169 4.4 81.5 1.0
CB B:VAL55 4.5 45.1 1.0
CB B:PRO32 4.5 57.4 1.0
O B:LEU53 4.5 43.5 1.0
N B:ALA54 4.5 35.9 1.0
C B:VAL55 4.5 46.6 1.0
CG2 B:VAL55 4.6 44.9 1.0
O B:HOH2014 4.8 49.4 1.0
N B:PRO33 4.9 62.4 1.0
CD B:ARG169 4.9 71.4 1.0
C B:LEU53 4.9 38.7 1.0
CA B:PRO32 5.0 57.8 1.0
O B:ALA54 5.0 37.2 1.0

Reference:

M.Zuehlsdorf, S.Werten, B.G.Klupp, G.J.Palm, T.Mettenleiter, W.Hinrichs. Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin PUL26N, A Herpesvirus Serine Protease Plos Pathog. V. 11 5045 2015.
ISSN: ISSN 1553-7366
PubMed: 26161660
DOI: 10.1371/JOURNAL.PPAT.1005045
Page generated: Fri Jul 26 02:37:46 2024

Last articles

Ca in 2W9D
Ca in 2W94
Ca in 2W87
Ca in 2W86
Ca in 2W7P
Ca in 2W7O
Ca in 2W67
Ca in 2W68
Ca in 2W4Z
Ca in 2W4Y
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy