Chlorine in PDB 4wgk: Crystal Structure of Human Neutral Ceramidase with Zn-Bound Phosphate

Enzymatic activity of Crystal Structure of Human Neutral Ceramidase with Zn-Bound Phosphate

All present enzymatic activity of Crystal Structure of Human Neutral Ceramidase with Zn-Bound Phosphate:
3.5.1.23;

Protein crystallography data

The structure of Crystal Structure of Human Neutral Ceramidase with Zn-Bound Phosphate, PDB code: 4wgk was solved by M.V.Airola, M.J.Pulkoski-Gross, L.M.Obeid, Y.A.Hannun, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

*Resolution Low / High (Å)*	68.65 / 2.58
*Space group*	P 1 2₁ 1
*Cell size a, b, c (Å), α, β, γ (°)*	73.480, 156.630, 80.330, 90.00, 108.04, 90.00
*R / R_free (%)*	17.8 / 22.3

Other elements in 4wgk:

The structure of Crystal Structure of Human Neutral Ceramidase with Zn-Bound Phosphate also contains other interesting chemical elements:

Zinc	(Zn)	2 atoms
Calcium	(Ca)	2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Human Neutral Ceramidase with Zn-Bound Phosphate (pdb code 4wgk). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human Neutral Ceramidase with Zn-Bound Phosphate, PDB code: 4wgk:

Chlorine binding site 1 out of 1 in 4wgk

Go back to

Chlorine Binding Sites List in 4wgk

Chlorine binding site 1 out of 1 in the Crystal Structure of Human Neutral Ceramidase with Zn-Bound Phosphate

Mono view

Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human Neutral Ceramidase with Zn-Bound Phosphate within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
B:Cl809 b:56.3 occ:1.00	OG	B:SER425	3.1	39.2	1.0
	NH2	B:ARG184	3.5	26.9	1.0
	O	B:ARG152	3.9	31.4	1.0
	CB	B:SER425	4.1	32.8	1.0
	CA	B:ASN151	4.1	51.3	1.0
	CB	B:ASN187	4.1	20.8	1.0
	C	B:ASN151	4.2	43.0	1.0
	OD1	B:ASN151	4.3	67.7	1.0
	CB	B:ASN151	4.3	59.3	1.0
	N	B:SER425	4.4	25.7	1.0
	OD2	B:ASP186	4.4	26.8	1.0
	O	B:ASN151	4.4	42.5	1.0
	C8	B:NAG807	4.5	68.0	1.0
	C	B:ALA424	4.6	23.2	1.0
	CG	B:ASN151	4.6	68.3	1.0
	N	B:ARG152	4.6	36.5	1.0
	CA	B:ALA424	4.7	24.1	1.0
	CG2	B:THR153	4.7	31.8	1.0
	CZ	B:ARG184	4.8	28.8	1.0
	C	B:ARG152	4.8	32.7	1.0
	CA	B:SER425	4.8	27.5	1.0
	O	B:HOH973	4.8	23.6	1.0
	CG	B:ASN187	4.9	23.7	1.0
	ND2	B:ASN187	4.9	21.6	1.0

Reference:

M.V.Airola, W.J.Allen, M.J.Pulkoski-Gross, L.M.Obeid, R.C.Rizzo, Y.A.Hannun. Structural Basis For Ceramide Recognition and Hydrolysis By Human Neutral Ceramidase. Structure V. 23 1482 2015.
ISSN: ISSN 0969-2126
PubMed: 26190575
DOI: 10.1016/J.STR.2015.06.013

Page generated: Fri Jul 11 22:30:58 2025

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO

	© Copyright 2008-2020 by atomistry.com
Home \| Site Map \| Copyright \| Contact us \| Privacy