Atomistry » Chlorine » PDB 4wl6-4ws6 » 4wpi
Atomistry »
  Chlorine »
    PDB 4wl6-4ws6 »
      4wpi »

Chlorine in PDB 4wpi: Crystal Structure of USP7 Ubiquitin-Like Domains in Extended Conformation

Enzymatic activity of Crystal Structure of USP7 Ubiquitin-Like Domains in Extended Conformation

All present enzymatic activity of Crystal Structure of USP7 Ubiquitin-Like Domains in Extended Conformation:
3.4.19.12;

Protein crystallography data

The structure of Crystal Structure of USP7 Ubiquitin-Like Domains in Extended Conformation, PDB code: 4wpi was solved by R.Pfoh, I.K.L.Lacdao, V.Saridakis, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 30.00 / 3.40
Space group P 42 21 2
Cell size a, b, c (Å), α, β, γ (°) 164.990, 164.990, 110.120, 90.00, 90.00, 90.00
R / Rfree (%) 24.1 / 28.2

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of USP7 Ubiquitin-Like Domains in Extended Conformation (pdb code 4wpi). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of USP7 Ubiquitin-Like Domains in Extended Conformation, PDB code: 4wpi:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in 4wpi

Go back to Chlorine Binding Sites List in 4wpi
Chlorine binding site 1 out of 3 in the Crystal Structure of USP7 Ubiquitin-Like Domains in Extended Conformation


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of USP7 Ubiquitin-Like Domains in Extended Conformation within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl2001

b:0.1
occ:1.00
NH2 A:ARG829 4.1 0.9 1.0
CB A:PHE809 4.2 0.0 1.0
CG A:PHE809 4.7 0.7 1.0

Chlorine binding site 2 out of 3 in 4wpi

Go back to Chlorine Binding Sites List in 4wpi
Chlorine binding site 2 out of 3 in the Crystal Structure of USP7 Ubiquitin-Like Domains in Extended Conformation


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of USP7 Ubiquitin-Like Domains in Extended Conformation within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl2002

b:0.8
occ:1.00
NE A:ARG697 2.5 0.8 1.0
CD A:ARG697 3.0 0.7 1.0
CZ A:ARG697 3.2 0.9 1.0
NH2 A:ARG697 3.6 0.4 1.0
CG A:GLU779 3.9 0.3 1.0
NH1 A:ARG697 4.0 0.2 1.0
CB A:GLU779 4.0 0.3 1.0
CG A:ARG697 4.4 0.9 1.0
CB A:ARG697 4.8 0.1 1.0
CD A:GLU779 5.0 0.6 1.0

Chlorine binding site 3 out of 3 in 4wpi

Go back to Chlorine Binding Sites List in 4wpi
Chlorine binding site 3 out of 3 in the Crystal Structure of USP7 Ubiquitin-Like Domains in Extended Conformation


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of USP7 Ubiquitin-Like Domains in Extended Conformation within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl2001

b:0.7
occ:1.00
NH1 B:ARG788 2.5 0.4 1.0
NH1 B:ARG816 2.8 0.2 1.0
NE2 B:HIS792 3.4 0.3 1.0
CZ B:ARG788 3.6 0.5 1.0
CZ B:ARG816 3.7 0.1 1.0
CD B:ARG788 3.8 0.3 1.0
CD B:ARG816 3.9 0.7 1.0
NE B:ARG788 4.1 0.2 1.0
CG B:ARG788 4.1 0.4 1.0
NE B:ARG816 4.1 0.0 1.0
CD2 B:HIS792 4.2 0.7 1.0
OD1 B:ASN741 4.2 0.8 1.0
CE1 B:HIS792 4.4 0.4 1.0
NH2 B:ARG788 4.6 0.5 1.0
NH2 B:ARG816 4.7 0.9 1.0
CB B:ARG788 4.7 0.8 1.0
ND2 B:ASN741 4.9 0.1 1.0

Reference:

R.Pfoh, I.K.Lacdao, A.A.Georges, A.Capar, H.Zheng, L.Frappier, V.Saridakis. Crystal Structure of USP7 Ubiquitin-Like Domains with An ICP0 Peptide Reveals A Novel Mechanism Used By Viral and Cellular Proteins to Target USP7. Plos Pathog. V. 11 04950 2015.
ISSN: ESSN 1553-7374
PubMed: 26046769
DOI: 10.1371/JOURNAL.PPAT.1004950
Page generated: Fri Jul 26 03:01:16 2024

Last articles

Cl in 3MOR
Cl in 3MNV
Cl in 3MMZ
Cl in 3MNA
Cl in 3MNF
Cl in 3MMX
Cl in 3MMK
Cl in 3MML
Cl in 3MMD
Cl in 3MMF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy