Atomistry » Chlorine » PDB 4ydq-4ylc » 4yl0
Atomistry »
  Chlorine »
    PDB 4ydq-4ylc »
      4yl0 »

Chlorine in PDB 4yl0: Crystal Structures of Mpges-1 Inhibitor Complexes

Enzymatic activity of Crystal Structures of Mpges-1 Inhibitor Complexes

All present enzymatic activity of Crystal Structures of Mpges-1 Inhibitor Complexes:
5.3.99.3;

Protein crystallography data

The structure of Crystal Structures of Mpges-1 Inhibitor Complexes, PDB code: 4yl0 was solved by J.G.Luz, S.Antonysamy, S.L.Kuklish, M.J.Fisher, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 30.00 / 1.52
Space group H 3
Cell size a, b, c (Å), α, β, γ (°) 76.621, 76.621, 123.092, 90.00, 90.00, 120.00
R / Rfree (%) 19.6 / 22

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structures of Mpges-1 Inhibitor Complexes (pdb code 4yl0). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structures of Mpges-1 Inhibitor Complexes, PDB code: 4yl0:

Chlorine binding site 1 out of 1 in 4yl0

Go back to Chlorine Binding Sites List in 4yl0
Chlorine binding site 1 out of 1 in the Crystal Structures of Mpges-1 Inhibitor Complexes


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structures of Mpges-1 Inhibitor Complexes within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl201

b:65.6
occ:1.00
CL A:4DZ201 0.0 65.6 1.0
C22 A:4DZ201 1.7 54.0 1.0
C11 A:4DZ201 2.7 40.9 1.0
C12 A:4DZ201 2.7 43.1 1.0
C10 A:4DZ201 4.0 40.2 1.0
C18 A:4DZ201 4.0 42.9 1.0
CG2 A:VAL128 4.2 27.2 1.0
C17 A:4DZ201 4.5 36.9 1.0
CG2 A:THR131 4.5 26.5 1.0
CB A:THR131 4.7 22.5 1.0
OG1 A:THR131 4.8 24.8 1.0
CA A:VAL128 4.9 23.3 1.0
CG1 A:VAL128 4.9 28.0 1.0
CB A:VAL128 4.9 23.2 1.0

Reference:

J.G.Luz, S.Antonysamy, S.L.Kuklish, B.Condon, M.R.Lee, D.Allison, X.P.Yu, S.Chandrasekhar, R.Backer, A.Zhang, M.Russell, S.S.Chang, A.Harvey, A.V.Sloan, M.J.Fisher. Crystal Structures of Mpges-1 Inhibitor Complexes Form A Basis For the Rational Design of Potent Analgesic and Anti-Inflammatory Therapeutics. J.Med.Chem. V. 58 4727 2015.
ISSN: ISSN 0022-2623
PubMed: 25961169
DOI: 10.1021/ACS.JMEDCHEM.5B00330
Page generated: Fri Jul 26 04:09:44 2024

Last articles

Cl in 3NDX
Cl in 3NCZ
Cl in 3NDH
Cl in 3ND0
Cl in 3NCP
Cl in 3NCR
Cl in 3NCQ
Cl in 3NCF
Cl in 3NBU
Cl in 3NCB
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy