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Atomistry » Chlorine » PDB 5aoa-5b1k » 5ap5 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 5aoa-5b1k » 5ap5 » |
Chlorine in PDB 5ap5: Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance.Enzymatic activity of Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance.
All present enzymatic activity of Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance.:
2.7.12.1; Protein crystallography data
The structure of Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance., PDB code: 5ap5
was solved by
M.D.Gurden,
I.M.Westwood,
A.Faisal,
S.Naud,
K.J.Cheung,
C.Mcandrew,
A.Wood,
J.Schmitt,
K.Boxall,
G.Mak,
P.Workman,
R.Burke,
S.Hoelder,
J.Blagg,
R.L.M.Van Montfort,
S.Linardopoulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance.
(pdb code 5ap5). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance., PDB code: 5ap5: Chlorine binding site 1 out of 1 in 5ap5Go back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance.
![]() Mono view ![]() Stereo pair view
Reference:
M.D.Gurden,
I.M.Westwood,
A.Faisal,
S.Naud,
K.J.Cheung,
C.Mcandrew,
A.Wood,
J.Schmitt,
K.Boxall,
G.Mak,
P.Workman,
R.Burke,
S.Hoelder,
J.Blagg,
R.L.M.Van Montfort,
S.Linardopoulos.
Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance. Cancer Res. V. 75 3340 2015.
Page generated: Fri Jul 26 05:23:01 2024
ISSN: ISSN 0008-5472 PubMed: 26202014 DOI: 10.1158/0008-5472.CAN-14-3272 |
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