Chlorine in PDB 5cgf: Yeast 20S Proteasome BETA5-G48C Mutant

All present enzymatic activity of Yeast 20S Proteasome BETA5-G48C Mutant:
3.4.25.1;

The structure of Yeast 20S Proteasome BETA5-G48C Mutant, PDB code: 5cgf was solved by C.Dubiella, M.Groll, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	15.00 / 2.80
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	135.460, 300.960, 143.860, 90.00, 112.88, 90.00
R / Rfree (%)	18.6 / 20.1

The structure of Yeast 20S Proteasome BETA5-G48C Mutant also contains other interesting chemical elements:

Magnesium

(Mg)

8 atoms

The binding sites of Chlorine atom in the Yeast 20S Proteasome BETA5-G48C Mutant (pdb code 5cgf). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Yeast 20S Proteasome BETA5-G48C Mutant, PDB code: 5cgf:

Chlorine binding site 1 out of 1 in the Yeast 20S Proteasome BETA5-G48C Mutant


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Yeast 20S Proteasome BETA5-G48C Mutant within 5.0Å range: probe atom residue distance (Å) B Occ G:Cl302 b:37.2 occ:1.00 NH1 G:ARG111 3.0 42.7 1.0 OH H:TYR69 3.0 40.3 1.0 OD1 G:ASN114 3.2 42.0 1.0 CB G:ASN114 3.7 37.1 1.0 CD G:ARG111 3.7 41.1 1.0 CG G:ASN114 3.8 38.3 1.0 CE2 H:TYR69 3.8 39.5 1.0 CZ H:TYR69 3.8 39.6 1.0 CZ G:ARG111 4.0 42.5 1.0 NE G:ARG111 4.3 42.5 1.0 CA G:ARG111 4.7 39.0 1.0 O G:ARG111 4.8 40.4 1.0 CG G:ARG111 5.0 40.0 1.0

C.Dubiella, R.Baur, H.Cui, E.M.Huber, M.Groll. Selective Inhibition of the Immunoproteasome By Structure-Based Targeting of A Non-Catalytic Cysteine. Angew.Chem.Int.Ed.Engl. V. 54 15888 2015.
ISSN: ESSN 1521-3773
PubMed: 26563572
DOI: 10.1002/ANIE.201506631