Chlorine in PDB 5cir: Crystal Structure of Death Receptor 4 (DR4; TNFFRSF10A) Bound to Trail (TNFSF10)

The structure of Crystal Structure of Death Receptor 4 (DR4; TNFFRSF10A) Bound to Trail (TNFSF10), PDB code: 5cir was solved by S.Sheriff, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.60 / 3.00
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	84.600, 87.600, 107.700, 90.00, 90.00, 90.00
R / Rfree (%)	17.7 / 21.6

The structure of Crystal Structure of Death Receptor 4 (DR4; TNFFRSF10A) Bound to Trail (TNFSF10) also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

The binding sites of Chlorine atom in the Crystal Structure of Death Receptor 4 (DR4; TNFFRSF10A) Bound to Trail (TNFSF10) (pdb code 5cir). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Death Receptor 4 (DR4; TNFFRSF10A) Bound to Trail (TNFSF10), PDB code: 5cir:

Chlorine binding site 1 out of 1 in the Crystal Structure of Death Receptor 4 (DR4; TNFFRSF10A) Bound to Trail (TNFSF10)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Death Receptor 4 (DR4; TNFFRSF10A) Bound to Trail (TNFSF10) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl301 b:39.4 occ:1.00 ZN A:ZN301 2.2 37.6 1.0 SG B:CYS230 3.3 25.2 1.0 CB B:CYS230 3.5 23.2 1.0 CB A:CYS230 3.5 22.0 1.0 SG A:CYS230 3.5 25.0 1.0 SG D:CYS230 3.6 26.6 1.0 CB D:CYS230 3.6 23.6 1.0 CA A:CYS230 3.6 22.8 1.0 CA B:CYS230 3.7 24.8 1.0 CA D:CYS230 3.8 24.8 1.0 N A:CYS230 4.4 23.6 1.0 N D:CYS230 4.5 24.9 1.0 N B:CYS230 4.6 25.3 1.0 C A:CYS230 4.8 28.4 1.0 C B:CYS230 4.9 33.2 1.0 OH B:TYR240 4.9 34.4 1.0

V.Ramamurthy, A.P.Yamniuk, E.J.Lawrence, W.Yong, L.A.Schneeweis, L.Cheng, M.Murdock, M.J.Corbett, M.L.Doyle, S.Sheriff. The Structure of the Death Receptor 4-Tnf-Related Apoptosis-Inducing Ligand (DR4-Trail) Complex. Acta Crystallogr F Struct V. 71 1273 2015BIOL Commun.
ISSN: ESSN 2053-230X
PubMed: 26457518
DOI: 10.1107/S2053230X15016416