Chlorine in PDB 5d08: Crystal Structure of Selenomethionine-Labeled Epoxyqueuosine Reductase

All present enzymatic activity of Crystal Structure of Selenomethionine-Labeled Epoxyqueuosine Reductase:
1.17.99.6;

The structure of Crystal Structure of Selenomethionine-Labeled Epoxyqueuosine Reductase, PDB code: 5d08 was solved by D.P.Dowling, Z.D.Miles, C.Kohrer, V.Bandarian, C.L.Drennan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.41 / 1.75
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	84.301, 95.780, 111.175, 90.00, 90.00, 90.00
R / Rfree (%)	16.7 / 19.6

The structure of Crystal Structure of Selenomethionine-Labeled Epoxyqueuosine Reductase also contains other interesting chemical elements:

Cobalt	(Co)	2 atoms
Iron	(Fe)	16 atoms

The binding sites of Chlorine atom in the Crystal Structure of Selenomethionine-Labeled Epoxyqueuosine Reductase (pdb code 5d08). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Selenomethionine-Labeled Epoxyqueuosine Reductase, PDB code: 5d08:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Selenomethionine-Labeled Epoxyqueuosine Reductase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Selenomethionine-Labeled Epoxyqueuosine Reductase within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl507 b:56.1 occ:1.00 OE1 A:GLU125 3.8 68.1 1.0 CG2 A:ILE176 4.2 34.8 1.0 CD2 A:LEU6 4.2 34.1 1.0 CG1 A:ILE176 4.5 34.7 1.0 CD1 A:ILE127 4.5 39.2 1.0 CG2 A:VAL3 4.6 43.1 1.0 CG1 A:ILE127 4.7 36.2 1.0 CD A:GLU125 4.8 71.1 1.0 CB A:ILE176 4.9 35.0 1.0 CD1 A:ILE176 5.0 36.9 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Selenomethionine-Labeled Epoxyqueuosine Reductase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Selenomethionine-Labeled Epoxyqueuosine Reductase within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl505 b:52.7 occ:1.00 CD2 B:LEU6 4.0 31.6 1.0 CG2 B:ILE176 4.1 31.8 1.0 OE1 B:GLU125 4.2 66.5 1.0 CG2 B:VAL3 4.3 45.7 1.0 CG1 B:ILE176 4.5 30.4 1.0 CD1 B:ILE127 4.7 35.4 1.0 CB B:ILE176 4.8 31.2 1.0 CD B:GLU125 4.9 67.7 1.0 CG1 B:ILE127 4.9 35.9 1.0 OD1 B:ASN2 4.9 61.0 1.0 CD1 B:ILE176 5.0 34.2 1.0

D.P.Dowling, Z.D.Miles, C.Kohrer, S.J.Maiocco, S.J.Elliott, V.Bandarian, C.L.Drennan. Molecular Basis of Cobalamin-Dependent Rna Modification. Nucleic Acids Res. V. 44 9965 2016.
ISSN: ESSN 1362-4962
PubMed: 27638883
DOI: 10.1093/NAR/GKW806