Atomistry » Chlorine » PDB 5dtk-5e1z » 5dwz
Atomistry »
  Chlorine »
    PDB 5dtk-5e1z »
      5dwz »

Chlorine in PDB 5dwz: Structural and Functional Characterization of Pqsbc, A Condensing Enzyme in the Biosynthesis of the Pseudomonas Aeruginosa Quinolone Signal

Enzymatic activity of Structural and Functional Characterization of Pqsbc, A Condensing Enzyme in the Biosynthesis of the Pseudomonas Aeruginosa Quinolone Signal

All present enzymatic activity of Structural and Functional Characterization of Pqsbc, A Condensing Enzyme in the Biosynthesis of the Pseudomonas Aeruginosa Quinolone Signal:
2.3.1.180;

Protein crystallography data

The structure of Structural and Functional Characterization of Pqsbc, A Condensing Enzyme in the Biosynthesis of the Pseudomonas Aeruginosa Quinolone Signal, PDB code: 5dwz was solved by S.L.Drees, C.Li, F.Prasetya, M.Saleem, I.Dreveny, U.Hennecke, P.Williams, J.Emsley, S.Fetzner, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 144.84 / 2.04
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 78.486, 114.960, 289.675, 90.00, 90.00, 90.00
R / Rfree (%) 19 / 23.7

Other elements in 5dwz:

The structure of Structural and Functional Characterization of Pqsbc, A Condensing Enzyme in the Biosynthesis of the Pseudomonas Aeruginosa Quinolone Signal also contains other interesting chemical elements:

Sodium (Na) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Structural and Functional Characterization of Pqsbc, A Condensing Enzyme in the Biosynthesis of the Pseudomonas Aeruginosa Quinolone Signal (pdb code 5dwz). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structural and Functional Characterization of Pqsbc, A Condensing Enzyme in the Biosynthesis of the Pseudomonas Aeruginosa Quinolone Signal, PDB code: 5dwz:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 5dwz

Go back to Chlorine Binding Sites List in 5dwz
Chlorine binding site 1 out of 2 in the Structural and Functional Characterization of Pqsbc, A Condensing Enzyme in the Biosynthesis of the Pseudomonas Aeruginosa Quinolone Signal


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structural and Functional Characterization of Pqsbc, A Condensing Enzyme in the Biosynthesis of the Pseudomonas Aeruginosa Quinolone Signal within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl409

b:46.6
occ:1.00
 ND2 C:ASN109 3.0 44.9 1.0
O B:HOH612 3.1 39.2 1.0
CB C:ASN109 3.2 37.1 1.0
CA C:ASN109 3.2 31.1 1.0
NH2 B:ARG162 3.3 24.9 1.0
CG C:ASN109 3.5 45.0 1.0
O C:ASN109 3.6 28.4 1.0
O B:HOH615 3.7 29.0 1.0
C C:ASN109 3.7 29.8 1.0
CG C:PRO122 3.9 22.0 1.0
CA B:GLY267 4.1 23.1 1.0
NZ C:LYS113 4.1 53.8 1.0
OG C:SER112 4.3 35.3 1.0
N C:ASN109 4.5 26.2 1.0
CZ B:ARG162 4.6 24.1 1.0
CE C:LYS113 4.6 49.9 1.0
CB C:PRO122 4.6 22.0 1.0
OD1 C:ASN109 4.7 43.7 1.0
O B:GLY267 4.8 20.5 1.0
N C:VAL110 4.9 24.9 1.0
CG C:LYS113 5.0 34.6 1.0
C B:GLY267 5.0 23.3 1.0
O C:HOH642 5.0 36.5 1.0
CD C:PRO122 5.0 20.2 1.0

Chlorine binding site 2 out of 2 in 5dwz

Go back to Chlorine Binding Sites List in 5dwz
Chlorine binding site 2 out of 2 in the Structural and Functional Characterization of Pqsbc, A Condensing Enzyme in the Biosynthesis of the Pseudomonas Aeruginosa Quinolone Signal


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structural and Functional Characterization of Pqsbc, A Condensing Enzyme in the Biosynthesis of the Pseudomonas Aeruginosa Quinolone Signal within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl409

b:47.7
occ:0.80
 CB D:ASN109 3.1 48.7 1.0
CA D:ASN109 3.2 39.4 1.0
O D:HOH516 3.3 61.7 1.0
O D:ASN109 3.3 41.4 1.0
ND2 D:ASN109 3.4 59.1 1.0
C D:ASN109 3.5 39.4 1.0
NZ D:LYS113 3.6 49.6 1.0
CG D:ASN109 3.7 58.1 1.0
NH2 A:ARG162 3.9 29.4 1.0
O D:HOH515 4.0 25.8 1.0
CE D:LYS113 4.2 49.6 1.0
OG D:SER112 4.2 34.1 1.0
CA A:GLY267 4.3 27.9 1.0
CG D:PRO122 4.3 27.2 1.0
CD D:LYS113 4.5 45.3 1.0
CG D:LYS113 4.5 37.5 1.0
N D:ASN109 4.6 31.4 1.0
N D:VAL110 4.6 32.4 1.0
OD1 D:ASN109 4.8 52.9 1.0
CB D:PRO122 5.0 26.7 1.0

Reference:

S.L.Drees, C.Li, F.Prasetya, M.Saleem, I.Dreveny, P.Williams, U.Hennecke, J.Emsley, S.Fetzner. Pqsbc, A Condensing Enzyme in the Biosynthesis of the Pseudomonas Aeruginosa Quinolone Signal: Crystal Structure, Inhibition, and Reaction Mechanism. J.Biol.Chem. V. 291 6610 2016.
ISSN: ESSN 1083-351X
PubMed: 26811339
DOI: 10.1074/JBC.M115.708453
Page generated: Sat Jul 12 01:27:27 2025

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy