Atomistry » Chlorine » PDB 5f03-5f6q » 5f2l
Atomistry »
  Chlorine »
    PDB 5f03-5f6q »
      5f2l »

Chlorine in PDB 5f2l: Tagatose-1,6-Bisphosphate Aldolase From Streptococcus Pyogenes in Complex with Competitive Inhibitor Talitol-1,6-Bisphosphate

Enzymatic activity of Tagatose-1,6-Bisphosphate Aldolase From Streptococcus Pyogenes in Complex with Competitive Inhibitor Talitol-1,6-Bisphosphate

All present enzymatic activity of Tagatose-1,6-Bisphosphate Aldolase From Streptococcus Pyogenes in Complex with Competitive Inhibitor Talitol-1,6-Bisphosphate:
4.1.2.40;

Protein crystallography data

The structure of Tagatose-1,6-Bisphosphate Aldolase From Streptococcus Pyogenes in Complex with Competitive Inhibitor Talitol-1,6-Bisphosphate, PDB code: 5f2l was solved by C.Lowkam, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 45.19 / 1.76
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 63.966, 108.029, 237.423, 90.00, 90.00, 90.00
R / Rfree (%) 16.3 / 18.9

Other elements in 5f2l:

The structure of Tagatose-1,6-Bisphosphate Aldolase From Streptococcus Pyogenes in Complex with Competitive Inhibitor Talitol-1,6-Bisphosphate also contains other interesting chemical elements:

Calcium (Ca) 7 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Tagatose-1,6-Bisphosphate Aldolase From Streptococcus Pyogenes in Complex with Competitive Inhibitor Talitol-1,6-Bisphosphate (pdb code 5f2l). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Tagatose-1,6-Bisphosphate Aldolase From Streptococcus Pyogenes in Complex with Competitive Inhibitor Talitol-1,6-Bisphosphate, PDB code: 5f2l:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in 5f2l

Go back to Chlorine Binding Sites List in 5f2l
Chlorine binding site 1 out of 3 in the Tagatose-1,6-Bisphosphate Aldolase From Streptococcus Pyogenes in Complex with Competitive Inhibitor Talitol-1,6-Bisphosphate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Tagatose-1,6-Bisphosphate Aldolase From Streptococcus Pyogenes in Complex with Competitive Inhibitor Talitol-1,6-Bisphosphate within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl404

b:75.9
occ:1.00
H C:ARG29 2.2 83.8 1.0
O C:HOH754 2.4 53.3 1.0
H C:ALA31 2.5 93.9 1.0
HB2 C:ALA31 3.1 91.5 1.0
N C:ARG29 3.1 69.8 1.0
HA C:GLN28 3.2 78.2 1.0
H C:GLY30 3.2 94.0 1.0
HB3 C:ALA31 3.3 91.5 1.0
N C:ALA31 3.3 78.3 1.0
HB2 C:ARG29 3.5 89.7 1.0
HG21 C:THR94 3.5 70.5 1.0
N C:GLY30 3.6 78.3 1.0
CB C:ALA31 3.6 76.2 1.0
HB C:THR94 3.7 55.5 1.0
CA C:GLN28 3.9 65.1 1.0
CA C:ARG29 3.9 72.0 1.0
C C:ARG29 4.0 74.6 1.0
C C:GLN28 4.0 66.4 1.0
HB3 C:GLN28 4.0 77.8 1.0
HG3 C:GLN28 4.0 78.5 1.0
CA C:ALA31 4.1 77.9 1.0
CG2 C:THR94 4.2 58.8 1.0
HG22 C:THR94 4.2 70.5 1.0
CB C:ARG29 4.2 74.8 1.0
C C:GLY30 4.3 80.1 1.0
CA C:GLY30 4.3 81.4 1.0
HA3 C:GLY30 4.3 97.7 1.0
H C:LEU32 4.3 89.0 1.0
CB C:THR94 4.4 46.3 1.0
CB C:GLN28 4.4 64.8 1.0
HB1 C:ALA31 4.4 91.5 1.0
CG C:GLN28 4.7 65.4 1.0
HA C:ALA31 4.7 93.5 1.0
HE C:ARG29 4.8 88.6 1.0
HB3 C:ARG29 4.8 89.7 1.0
HA C:ARG29 4.8 86.4 1.0
O C:ARG29 4.9 73.8 1.0
OG1 C:THR94 4.9 43.8 1.0
N C:LEU32 5.0 74.1 1.0
HG2 C:GLN28 5.0 78.5 1.0

Chlorine binding site 2 out of 3 in 5f2l

Go back to Chlorine Binding Sites List in 5f2l
Chlorine binding site 2 out of 3 in the Tagatose-1,6-Bisphosphate Aldolase From Streptococcus Pyogenes in Complex with Competitive Inhibitor Talitol-1,6-Bisphosphate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Tagatose-1,6-Bisphosphate Aldolase From Streptococcus Pyogenes in Complex with Competitive Inhibitor Talitol-1,6-Bisphosphate within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl403

b:32.5
occ:0.35
H B:ALA31 1.8 59.7 1.0
H B:GLY30 2.6 52.5 1.0
N B:ALA31 2.6 49.7 1.0
N B:GLY30 2.9 43.8 1.0
HB2 B:ALA31 3.0 58.6 1.0
HA3 B:GLY30 3.1 57.5 1.0
CA B:GLY30 3.3 47.9 1.0
HB3 B:ALA31 3.3 58.6 1.0
C B:GLY30 3.4 49.3 1.0
HB B:THR94 3.4 42.8 1.0
CB B:ALA31 3.4 48.9 1.0
HG21 B:THR94 3.5 44.9 1.0
CA B:ALA31 3.6 50.5 1.0
C B:ARG29 3.6 39.8 1.0
N B:ARG29 3.6 33.0 1.0
HG1 B:THR94 3.7 46.3 1.0
HB2 B:ARG29 3.7 39.9 1.0
O B:HOH819 3.8 49.8 1.0
HH22 B:ARG34 3.8 75.3 1.0
CA B:ARG29 4.0 35.1 1.0
CB B:THR94 4.0 35.7 1.0
HA B:ALA31 4.0 60.6 1.0
O B:HOH525 4.0 44.1 1.0
CG2 B:THR94 4.1 37.4 1.0
HA2 B:GLY30 4.2 57.5 1.0
OG1 B:THR94 4.2 38.6 1.0
HH12 B:ARG34 4.2 76.3 1.0
H B:LEU32 4.3 58.2 1.0
CB B:ARG29 4.3 33.2 1.0
HG22 B:THR94 4.4 44.9 1.0
HB1 B:ALA31 4.4 58.6 1.0
NH2 B:ARG34 4.4 62.7 1.0
HA B:GLN28 4.4 37.1 1.0
O B:ARG29 4.4 40.9 1.0
O B:GLY30 4.5 51.2 1.0
HB3 B:GLN28 4.7 40.6 1.0
HB3 B:ARG29 4.7 39.9 1.0
C B:GLN28 4.7 31.4 1.0
NH1 B:ARG34 4.8 63.6 1.0
C B:ALA31 4.8 50.1 1.0
HH21 B:ARG34 4.8 75.3 1.0
N B:LEU32 4.9 48.5 1.0
CZ B:ARG34 4.9 64.2 1.0
HA B:ARG29 4.9 42.1 1.0
HG23 B:THR94 5.0 44.9 1.0
CA B:GLN28 5.0 30.9 1.0

Chlorine binding site 3 out of 3 in 5f2l

Go back to Chlorine Binding Sites List in 5f2l
Chlorine binding site 3 out of 3 in the Tagatose-1,6-Bisphosphate Aldolase From Streptococcus Pyogenes in Complex with Competitive Inhibitor Talitol-1,6-Bisphosphate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Tagatose-1,6-Bisphosphate Aldolase From Streptococcus Pyogenes in Complex with Competitive Inhibitor Talitol-1,6-Bisphosphate within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl402

b:73.1
occ:1.00
H D:ARG29 2.2 84.9 1.0
O D:HOH735 2.5 52.2 1.0
H D:ALA31 2.5 0.8 1.0
HB3 D:ALA31 3.0 96.3 1.0
HB2 D:ALA31 3.0 96.3 1.0
N D:ARG29 3.1 70.7 1.0
HA D:GLN28 3.1 78.1 1.0
N D:ALA31 3.4 86.5 1.0
H D:GLY30 3.4 96.4 1.0
HG21 D:THR94 3.4 67.0 1.0
CB D:ALA31 3.4 80.2 1.0
HB2 D:ARG29 3.6 89.8 1.0
N D:GLY30 3.7 80.3 1.0
HB D:THR94 3.8 60.2 1.0
HG3 D:GLN28 3.8 79.9 1.0
CA D:GLN28 3.9 65.0 1.0
CA D:ARG29 3.9 74.2 1.0
C D:GLN28 3.9 67.5 1.0
C D:ARG29 4.0 77.5 1.0
CA D:ALA31 4.0 85.4 1.0
HB3 D:GLN28 4.0 78.6 1.0
CG2 D:THR94 4.1 55.8 1.0
HG22 D:THR94 4.2 67.0 1.0
HB1 D:ALA31 4.3 96.3 1.0
CB D:ARG29 4.3 74.8 1.0
CB D:GLN28 4.3 65.5 1.0
H D:LEU32 4.3 0.5 1.0
C D:GLY30 4.4 86.5 1.0
CB D:THR94 4.4 50.2 1.0
CA D:GLY30 4.4 84.8 1.0
HA3 D:GLY30 4.4 0.7 1.0
CG D:GLN28 4.5 66.6 1.0
HH22 D:ARG34 4.5 0.5 1.0
HE D:ARG29 4.6 83.2 1.0
HA D:ALA31 4.6 0.4 1.0
HG2 D:GLN28 4.8 79.9 1.0
HA D:ARG29 4.8 89.0 1.0
O D:ARG29 4.8 78.0 1.0
OG1 D:THR94 4.8 48.9 1.0
HB3 D:ARG29 4.9 89.8 1.0
HG23 D:THR94 5.0 67.0 1.0
O D:ASP27 5.0 52.3 1.0
N D:LEU32 5.0 83.7 1.0

Reference:

C.Lowkam, B.Liotard, J.Sygusch. Non-Stereospecific Substrate Cleavage By Tagatose-Bisphosphate Class I Aldolase To Be Published.
Page generated: Sat Jul 12 01:53:54 2025

Last articles

F in 8SHD
F in 8SHA
F in 8SGL
F in 8SH9
F in 8SHC
F in 8SGC
F in 8SG9
F in 8SGI
F in 8SG8
F in 8SFF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy