Chlorine in PDB 5fbr: PI4KB in Complex with RAB11 and the MI359 Inhibitor

All present enzymatic activity of PI4KB in Complex with RAB11 and the MI359 Inhibitor:
2.7.1.67;

The structure of PI4KB in Complex with RAB11 and the MI359 Inhibitor, PDB code: 5fbr was solved by D.Chalupska, I.Mejdrova, R.Nencka, E.Boura, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.65 / 3.28
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	49.266, 103.937, 187.646, 90.00, 90.00, 90.00
R / Rfree (%)	22.5 / 26.4

The binding sites of Chlorine atom in the PI4KB in Complex with RAB11 and the MI359 Inhibitor (pdb code 5fbr). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the PI4KB in Complex with RAB11 and the MI359 Inhibitor, PDB code: 5fbr:

Chlorine binding site 1 out of 1 in the PI4KB in Complex with RAB11 and the MI359 Inhibitor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of PI4KB in Complex with RAB11 and the MI359 Inhibitor within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl801 b:0.7 occ:1.00 CL1 A:5W7801 0.0 0.7 1.0 C25 A:5W7801 1.8 0.8 1.0 N24 A:5W7801 2.7 0.4 1.0 C26 A:5W7801 2.8 0.5 1.0 C8 A:5W7801 3.5 0.8 1.0 N22 A:5W7801 4.1 0.2 1.0 C27 A:5W7801 4.1 0.1 1.0 CD2 A:LEU374 4.2 0.4 1.0 C12 A:5W7801 4.3 0.0 1.0 N1 A:5W7801 4.5 96.8 1.0 CD1 A:LEU374 4.6 96.8 1.0 C9 A:5W7801 4.6 97.3 1.0 C23 A:5W7801 4.6 0.5 1.0 CG A:LEU374 4.8 96.8 1.0 CB A:LEU374 5.0 0.2 1.0 C11 A:5W7801 5.0 0.2 1.0

D.Chalupska, I.Mejdrova, R.Nencka, E.Boura. PI4KB in Complex with RAB11 and the MI359 Inhibitor To Be Published.