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Atomistry » Chlorine » PDB 5h6g-5hi5 » 5hes | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 5h6g-5hi5 » 5hes » |
Chlorine in PDB 5hes: Human Leucine Zipper- and Sterile Alpha Motif-Containing Kinase (Zak, Mlt, Hccs-4, Mrk, Azk, Mltk) in Complex with VemurafenibEnzymatic activity of Human Leucine Zipper- and Sterile Alpha Motif-Containing Kinase (Zak, Mlt, Hccs-4, Mrk, Azk, Mltk) in Complex with Vemurafenib
All present enzymatic activity of Human Leucine Zipper- and Sterile Alpha Motif-Containing Kinase (Zak, Mlt, Hccs-4, Mrk, Azk, Mltk) in Complex with Vemurafenib:
2.7.11.25; Protein crystallography data
The structure of Human Leucine Zipper- and Sterile Alpha Motif-Containing Kinase (Zak, Mlt, Hccs-4, Mrk, Azk, Mltk) in Complex with Vemurafenib, PDB code: 5hes
was solved by
S.Mathea,
E.Salah,
K.R.Abdul Azeez,
C.Tallant,
M.Szklarz,
A.Chaikuad,
B.Shrestha,
F.J.Sorrell,
J.M.Elkins,
L.Shrestha,
N.Burgess-Brown,
F.Vondelft,
C.H.Arrowsmith,
A.M.Edwards,
C.Bountra,
S.Knapp,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5hes:
The structure of Human Leucine Zipper- and Sterile Alpha Motif-Containing Kinase (Zak, Mlt, Hccs-4, Mrk, Azk, Mltk) in Complex with Vemurafenib also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Human Leucine Zipper- and Sterile Alpha Motif-Containing Kinase (Zak, Mlt, Hccs-4, Mrk, Azk, Mltk) in Complex with Vemurafenib
(pdb code 5hes). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Human Leucine Zipper- and Sterile Alpha Motif-Containing Kinase (Zak, Mlt, Hccs-4, Mrk, Azk, Mltk) in Complex with Vemurafenib, PDB code: 5hes: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 5hesGo back to![]() ![]()
Chlorine binding site 1 out
of 2 in the Human Leucine Zipper- and Sterile Alpha Motif-Containing Kinase (Zak, Mlt, Hccs-4, Mrk, Azk, Mltk) in Complex with Vemurafenib
![]() Mono view ![]() Stereo pair view
Chlorine binding site 2 out of 2 in 5hesGo back to![]() ![]()
Chlorine binding site 2 out
of 2 in the Human Leucine Zipper- and Sterile Alpha Motif-Containing Kinase (Zak, Mlt, Hccs-4, Mrk, Azk, Mltk) in Complex with Vemurafenib
![]() Mono view ![]() Stereo pair view
Reference:
S.Mathea,
K.R.Abdul Azeez,
E.Salah,
C.Tallant,
F.Wolfreys,
R.Konietzny,
R.Fischer,
H.J.Lou,
P.E.Brennan,
G.Schnapp,
A.Pautsch,
B.M.Kessler,
B.E.Turk,
S.Knapp.
Structure of the Human Protein Kinase Zak in Complex with Vemurafenib. Acs Chem.Biol. V. 11 1595 2016.
Page generated: Fri Jul 26 08:48:47 2024
ISSN: ESSN 1554-8937 PubMed: 26999302 DOI: 10.1021/ACSCHEMBIO.6B00043 |
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