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Atomistry » Chlorine » PDB 5hi6-5hq4 » 5hls » |
Chlorine in PDB 5hls: Crystal Structure of the First Bromodomain of Human BRD4 Bound to Cpi- 0610Protein crystallography data
The structure of Crystal Structure of the First Bromodomain of Human BRD4 Bound to Cpi- 0610, PDB code: 5hls
was solved by
H.Jayaram,
F.Poy,
J.W.Setser,
S.F.Bellon,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of the First Bromodomain of Human BRD4 Bound to Cpi- 0610
(pdb code 5hls). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the First Bromodomain of Human BRD4 Bound to Cpi- 0610, PDB code: 5hls: Chlorine binding site 1 out of 1 in 5hlsGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Crystal Structure of the First Bromodomain of Human BRD4 Bound to Cpi- 0610
![]() Mono view ![]() Stereo pair view
Reference:
B.K.Albrecht,
V.S.Gehling,
M.C.Hewitt,
R.G.Vaswani,
A.Cote,
Y.Leblanc,
C.G.Nasveschuk,
S.Bellon,
L.Bergeron,
R.Campbell,
N.Cantone,
M.R.Cooper,
R.T.Cummings,
H.Jayaram,
S.Joshi,
J.A.Mertz,
A.Neiss,
E.Normant,
M.O'meara,
E.Pardo,
F.Poy,
P.Sandy,
J.Supko,
R.J.Sims,
J.C.Harmange,
A.M.Taylor,
J.E.Audia.
Identification of A Benzoisoxazoloazepine Inhibitor (Cpi-0610) of the Bromodomain and Extra-Terminal (Bet) Family As A Candidate For Human Clinical Trials. J.Med.Chem. V. 59 1330 2016.
Page generated: Fri Jul 26 08:53:22 2024
ISSN: ISSN 0022-2623 PubMed: 26815195 DOI: 10.1021/ACS.JMEDCHEM.5B01882 |
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