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Atomistry » Chlorine » PDB 5hi6-5hq4 » 5hlw | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 5hi6-5hq4 » 5hlw » |
Chlorine in PDB 5hlw: Crystal Structure of C-Met Mutant Y1230H in Complex with Compound 14Enzymatic activity of Crystal Structure of C-Met Mutant Y1230H in Complex with Compound 14
All present enzymatic activity of Crystal Structure of C-Met Mutant Y1230H in Complex with Compound 14:
2.7.10.1; Protein crystallography data
The structure of Crystal Structure of C-Met Mutant Y1230H in Complex with Compound 14, PDB code: 5hlw
was solved by
F.Vallee,
S.Pouzieux,
J.P.Marquette,
J.Houtmann,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of C-Met Mutant Y1230H in Complex with Compound 14
(pdb code 5hlw). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of C-Met Mutant Y1230H in Complex with Compound 14, PDB code: 5hlw: Chlorine binding site 1 out of 1 in 5hlwGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Crystal Structure of C-Met Mutant Y1230H in Complex with Compound 14
![]() Mono view ![]() Stereo pair view
Reference:
A.Ugolini,
M.Kenigsberg,
A.Rak,
F.Vallee,
J.Houtmann,
M.Lowinski,
C.Capdevila,
J.Khider,
E.Albert,
N.Martinet,
C.Nemecek,
S.Grapinet,
E.Bacque,
M.Roesner,
C.Delaisi,
L.Calvet,
F.Bonche,
D.Semiond,
C.Egile,
H.Goulaouic,
L.Schio.
Discovery and Pharmacokinetic and Pharmacological Properties of the Potent and Selective Met Kinase Inhibitor 1-{6-[6-(4-Fluorophenyl)-[1,2,4]Triazolo[4, 3-B]Pyridazin-3-Ylsulfanyl]Benzothiazol-2-Yl}-3-(2-Morpholin -4-Ylethyl)Urea (SAR125844). J.Med.Chem. V. 59 7066 2016.
Page generated: Sat Jul 12 02:49:25 2025
ISSN: ISSN 0022-2623 PubMed: 27355974 DOI: 10.1021/ACS.JMEDCHEM.6B00280 |
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