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Atomistry » Chlorine » PDB 5ivs-5j7f » 5iwi | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 5ivs-5j7f » 5iwi » |
Chlorine in PDB 5iwi: 1.98A Structure of GSK945237 with S.Aureus Dna Gyrase and Singly Nicked DnaEnzymatic activity of 1.98A Structure of GSK945237 with S.Aureus Dna Gyrase and Singly Nicked Dna
All present enzymatic activity of 1.98A Structure of GSK945237 with S.Aureus Dna Gyrase and Singly Nicked Dna:
5.99.1.3; Protein crystallography data
The structure of 1.98A Structure of GSK945237 with S.Aureus Dna Gyrase and Singly Nicked Dna, PDB code: 5iwi
was solved by
B.D.Bax,
T.J.Miles,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5iwi:
The structure of 1.98A Structure of GSK945237 with S.Aureus Dna Gyrase and Singly Nicked Dna also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the 1.98A Structure of GSK945237 with S.Aureus Dna Gyrase and Singly Nicked Dna
(pdb code 5iwi). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the 1.98A Structure of GSK945237 with S.Aureus Dna Gyrase and Singly Nicked Dna, PDB code: 5iwi: Chlorine binding site 1 out of 1 in 5iwiGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the 1.98A Structure of GSK945237 with S.Aureus Dna Gyrase and Singly Nicked Dna
![]() Mono view ![]() Stereo pair view
Reference:
T.J.Miles,
A.J.Hennessy,
B.Bax,
G.Brooks,
B.S.Brown,
P.Brown,
N.Cailleau,
D.Chen,
S.Dabbs,
D.T.Davies,
J.M.Esken,
I.Giordano,
J.L.Hoover,
G.E.Jones,
S.K.Kusalakumari Sukmar,
R.E.Markwell,
E.A.Minthorn,
S.Rittenhouse,
M.N.Gwynn,
N.D.Pearson.
Novel Tricyclics (E.G., GSK945237) As Potent Inhibitors of Bacterial Type Iia Topoisomerases. Bioorg.Med.Chem.Lett. V. 26 2464 2016.
Page generated: Sat Jul 12 03:19:36 2025
ISSN: ESSN 1464-3405 PubMed: 27055939 DOI: 10.1016/J.BMCL.2016.03.106 |
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