Chlorine »
PDB 5jkd-5jsv »
5jsv »
Chlorine in PDB 5jsv: Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-((((3AR,4R,6R,6AR)-6-Methoxy-2,2-Dimethyltetrahydrofuro[3,4- D][1,3]Dioxol-4-Yl)Methyl)Amino)-1H-Imidazo[4,5-G]Quinazolin-8(7H)- One
Enzymatic activity of Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-((((3AR,4R,6R,6AR)-6-Methoxy-2,2-Dimethyltetrahydrofuro[3,4- D][1,3]Dioxol-4-Yl)Methyl)Amino)-1H-Imidazo[4,5-G]Quinazolin-8(7H)- One
All present enzymatic activity of Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-((((3AR,4R,6R,6AR)-6-Methoxy-2,2-Dimethyltetrahydrofuro[3,4- D][1,3]Dioxol-4-Yl)Methyl)Amino)-1H-Imidazo[4,5-G]Quinazolin-8(7H)- One:
2.4.2.29;
2.4.2.29;
Protein crystallography data
The structure of Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-((((3AR,4R,6R,6AR)-6-Methoxy-2,2-Dimethyltetrahydrofuro[3,4- D][1,3]Dioxol-4-Yl)Methyl)Amino)-1H-Imidazo[4,5-G]Quinazolin-8(7H)- One, PDB code: 5jsv
was solved by
F.R.Ehrmann,
D.Nguyen,
A.Heine,
G.Klebe,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 39.95 / 1.17 |
| Space group | C 1 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 90.505, 65.200, 70.598, 90.00, 96.44, 90.00 |
| R / Rfree (%) | 12.1 / 13.9 |
Other elements in 5jsv:
The structure of Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-((((3AR,4R,6R,6AR)-6-Methoxy-2,2-Dimethyltetrahydrofuro[3,4- D][1,3]Dioxol-4-Yl)Methyl)Amino)-1H-Imidazo[4,5-G]Quinazolin-8(7H)- One also contains other interesting chemical elements:
| Zinc | (Zn) | 1 atom |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-((((3AR,4R,6R,6AR)-6-Methoxy-2,2-Dimethyltetrahydrofuro[3,4- D][1,3]Dioxol-4-Yl)Methyl)Amino)-1H-Imidazo[4,5-G]Quinazolin-8(7H)- One
(pdb code 5jsv). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-((((3AR,4R,6R,6AR)-6-Methoxy-2,2-Dimethyltetrahydrofuro[3,4- D][1,3]Dioxol-4-Yl)Methyl)Amino)-1H-Imidazo[4,5-G]Quinazolin-8(7H)- One, PDB code: 5jsv:
In total only one binding site of Chlorine was determined in the Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-((((3AR,4R,6R,6AR)-6-Methoxy-2,2-Dimethyltetrahydrofuro[3,4- D][1,3]Dioxol-4-Yl)Methyl)Amino)-1H-Imidazo[4,5-G]Quinazolin-8(7H)- One, PDB code: 5jsv:
Chlorine binding site 1 out of 1 in 5jsv
Go back to
Chlorine Binding Sites List in 5jsv
Chlorine binding site 1 out
of 1 in the Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-((((3AR,4R,6R,6AR)-6-Methoxy-2,2-Dimethyltetrahydrofuro[3,4- D][1,3]Dioxol-4-Yl)Methyl)Amino)-1H-Imidazo[4,5-G]Quinazolin-8(7H)- One
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-((((3AR,4R,6R,6AR)-6-Methoxy-2,2-Dimethyltetrahydrofuro[3,4- D][1,3]Dioxol-4-Yl)Methyl)Amino)-1H-Imidazo[4,5-G]Quinazolin-8(7H)- One within 5.0Å range:
|
Reference:
F.R.Ehrmann,
E.Schaefer,
A.Heine,
F.Diederich,
G.Klebe.
Application of Carbohydrates Based Lin-Benzoguanines in A Solvent-Exposed Subpocket of the Trna-Modifying Enzyme Tgt To Be Published.
Page generated: Sat Jul 12 03:44:56 2025
Last articles
Mg in 4JHDMg in 4JH6
Mg in 4JH8
Mg in 4JH7
Mg in 4JH3
Mg in 4JH5
Mg in 4JF2
Mg in 4JH2
Mg in 4JH1
Mg in 4JEJ
