Chlorine »
PDB 5l5b-5l7f »
5l5i »
Chlorine in PDB 5l5i: Yeast 20S Proteasome with Human BETA5I (1-138) and Human BETA6 (97- 111; 118-133) in Complex with Epoxyketone Inhibitor 9
Enzymatic activity of Yeast 20S Proteasome with Human BETA5I (1-138) and Human BETA6 (97- 111; 118-133) in Complex with Epoxyketone Inhibitor 9
All present enzymatic activity of Yeast 20S Proteasome with Human BETA5I (1-138) and Human BETA6 (97- 111; 118-133) in Complex with Epoxyketone Inhibitor 9:
3.4.25.1;
3.4.25.1;
Protein crystallography data
The structure of Yeast 20S Proteasome with Human BETA5I (1-138) and Human BETA6 (97- 111; 118-133) in Complex with Epoxyketone Inhibitor 9, PDB code: 5l5i
was solved by
M.Groll,
E.M.Huber,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 15.00 / 2.90 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 135.710, 299.420, 145.970, 90.00, 112.82, 90.00 |
| R / Rfree (%) | 17.6 / 21 |
Other elements in 5l5i:
The structure of Yeast 20S Proteasome with Human BETA5I (1-138) and Human BETA6 (97- 111; 118-133) in Complex with Epoxyketone Inhibitor 9 also contains other interesting chemical elements:
| Magnesium | (Mg) | 8 atoms |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Yeast 20S Proteasome with Human BETA5I (1-138) and Human BETA6 (97- 111; 118-133) in Complex with Epoxyketone Inhibitor 9
(pdb code 5l5i). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Yeast 20S Proteasome with Human BETA5I (1-138) and Human BETA6 (97- 111; 118-133) in Complex with Epoxyketone Inhibitor 9, PDB code: 5l5i:
Jump to Chlorine binding site number: 1; 2;
In total 2 binding sites of Chlorine where determined in the Yeast 20S Proteasome with Human BETA5I (1-138) and Human BETA6 (97- 111; 118-133) in Complex with Epoxyketone Inhibitor 9, PDB code: 5l5i:
Jump to Chlorine binding site number: 1; 2;
Chlorine binding site 1 out of 2 in 5l5i
Go back to
Chlorine Binding Sites List in 5l5i
Chlorine binding site 1 out
of 2 in the Yeast 20S Proteasome with Human BETA5I (1-138) and Human BETA6 (97- 111; 118-133) in Complex with Epoxyketone Inhibitor 9
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Yeast 20S Proteasome with Human BETA5I (1-138) and Human BETA6 (97- 111; 118-133) in Complex with Epoxyketone Inhibitor 9 within 5.0Å range:
|
Chlorine binding site 2 out of 2 in 5l5i
Go back to
Chlorine Binding Sites List in 5l5i
Chlorine binding site 2 out
of 2 in the Yeast 20S Proteasome with Human BETA5I (1-138) and Human BETA6 (97- 111; 118-133) in Complex with Epoxyketone Inhibitor 9
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 2 of Yeast 20S Proteasome with Human BETA5I (1-138) and Human BETA6 (97- 111; 118-133) in Complex with Epoxyketone Inhibitor 9 within 5.0Å range:
|
Reference:
E.M.Huber,
W.Heinemeyer,
G.De Bruin,
H.S.Overkleeft,
M.Groll.
A Humanized Yeast Proteasome Identifies Unique Binding Modes of Inhibitors For the Immunosubunit Beta 5I. Embo J. V. 35 2602 2016.
ISSN: ESSN 1460-2075
PubMed: 27789522
DOI: 10.15252/EMBJ.201695222
Page generated: Sat Jul 12 04:23:06 2025
ISSN: ESSN 1460-2075
PubMed: 27789522
DOI: 10.15252/EMBJ.201695222
Last articles
Mg in 1SO2Mg in 1SO5
Mg in 1SO4
Mg in 1SO3
Mg in 1SNF
Mg in 1SLH
Mg in 1SL2
Mg in 1SL5
Mg in 1SKR
Mg in 1SL0
