Atomistry » Chlorine » PDB 5luj-5lzm » 5lvk
Atomistry »
  Chlorine »
    PDB 5luj-5lzm »
      5lvk »

Chlorine in PDB 5lvk: Human Lysozyme Soaked with [H2IND][Trans-RUCL4(Dmso)(Hind)]

Enzymatic activity of Human Lysozyme Soaked with [H2IND][Trans-RUCL4(Dmso)(Hind)]

All present enzymatic activity of Human Lysozyme Soaked with [H2IND][Trans-RUCL4(Dmso)(Hind)]:
3.2.1.17;

Protein crystallography data

The structure of Human Lysozyme Soaked with [H2IND][Trans-RUCL4(Dmso)(Hind)], PDB code: 5lvk was solved by K.Kurpiewska, A.Szura, K.Lewinski, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 14.37 / 2.49
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 42.039, 64.100, 111.311, 90.00, 90.00, 90.00
R / Rfree (%) 17.7 / 28.1

Other elements in 5lvk:

The structure of Human Lysozyme Soaked with [H2IND][Trans-RUCL4(Dmso)(Hind)] also contains other interesting chemical elements:

Ruthenium (Ru) 2 atoms
Sodium (Na) 3 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Human Lysozyme Soaked with [H2IND][Trans-RUCL4(Dmso)(Hind)] (pdb code 5lvk). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 5 binding sites of Chlorine where determined in the Human Lysozyme Soaked with [H2IND][Trans-RUCL4(Dmso)(Hind)], PDB code: 5lvk:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5;

Chlorine binding site 1 out of 5 in 5lvk

Go back to Chlorine Binding Sites List in 5lvk
Chlorine binding site 1 out of 5 in the Human Lysozyme Soaked with [H2IND][Trans-RUCL4(Dmso)(Hind)]


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Lysozyme Soaked with [H2IND][Trans-RUCL4(Dmso)(Hind)] within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl204

b:26.8
occ:1.00
 O A:HOH322 3.6 12.8 1.0
N A:ASN60 3.6 11.4 1.0
NE1 A:TRP64 3.7 12.7 1.0
CD1 A:TRP64 3.7 8.1 1.0
NE1 A:TRP109 3.9 13.8 1.0
CB A:ASN60 3.9 11.5 1.0
O A:GLN58 4.1 11.8 1.0
CA A:ILE59 4.1 7.9 1.0
CD1 A:TRP109 4.3 11.2 1.0
CE2 A:TRP109 4.4 10.1 1.0
C A:ILE59 4.4 7.7 1.0
O A:HOH395 4.4 19.9 1.0
CA A:ASN60 4.4 14.8 1.0
CZ2 A:TRP109 4.8 10.5 1.0
CE2 A:TRP64 4.8 9.1 1.0
CG A:TRP64 4.9 9.0 1.0
CG A:TRP109 4.9 8.3 1.0
CB A:ILE59 4.9 12.3 1.0
CG2 A:ILE59 5.0 6.5 1.0
OD1 A:ASP53 5.0 7.7 1.0

Chlorine binding site 2 out of 5 in 5lvk

Go back to Chlorine Binding Sites List in 5lvk
Chlorine binding site 2 out of 5 in the Human Lysozyme Soaked with [H2IND][Trans-RUCL4(Dmso)(Hind)]


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Human Lysozyme Soaked with [H2IND][Trans-RUCL4(Dmso)(Hind)] within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl205

b:41.8
occ:1.00
 NH2 B:ARG115 3.9 21.9 1.0
O B:HOH398 3.9 14.8 1.0
NH2 A:ARG98 4.0 8.2 1.0
CB A:ALA76 4.9 7.4 1.0

Chlorine binding site 3 out of 5 in 5lvk

Go back to Chlorine Binding Sites List in 5lvk
Chlorine binding site 3 out of 5 in the Human Lysozyme Soaked with [H2IND][Trans-RUCL4(Dmso)(Hind)]


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Human Lysozyme Soaked with [H2IND][Trans-RUCL4(Dmso)(Hind)] within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl206

b:35.6
occ:1.00
 NH1 A:ARG119 3.6 13.8 1.0
NH2 A:ARG119 4.3 19.6 1.0
CZ A:ARG119 4.4 13.1 1.0
O A:HOH308 4.6 9.3 1.0

Chlorine binding site 4 out of 5 in 5lvk

Go back to Chlorine Binding Sites List in 5lvk
Chlorine binding site 4 out of 5 in the Human Lysozyme Soaked with [H2IND][Trans-RUCL4(Dmso)(Hind)]


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Human Lysozyme Soaked with [H2IND][Trans-RUCL4(Dmso)(Hind)] within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl207

b:27.7
occ:1.00
 O A:HOH389 2.8 29.9 1.0
N A:GLY127 3.3 19.3 1.0
OE1 A:GLN126 3.8 45.9 1.0
CA A:GLY127 3.9 18.8 1.0
N A:GLY129 4.1 15.4 1.0
C A:GLN126 4.3 26.3 1.0
CA A:GLN126 4.3 27.0 1.0
N A:CYS128 4.4 20.1 1.0
C A:GLY127 4.4 25.0 1.0
CA A:GLY129 4.6 9.9 1.0
CB A:GLN126 4.7 26.7 1.0
CD A:GLN126 4.9 55.1 1.0

Chlorine binding site 5 out of 5 in 5lvk

Go back to Chlorine Binding Sites List in 5lvk
Chlorine binding site 5 out of 5 in the Human Lysozyme Soaked with [H2IND][Trans-RUCL4(Dmso)(Hind)]


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Human Lysozyme Soaked with [H2IND][Trans-RUCL4(Dmso)(Hind)] within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl203

b:27.9
occ:1.00
 NE1 B:TRP109 3.7 7.3 1.0
NE1 B:TRP64 3.7 8.3 1.0
CD1 B:TRP64 3.8 10.2 1.0
N B:ASN60 4.0 10.8 1.0
CD1 B:TRP109 4.1 11.6 1.0
CE2 B:TRP109 4.1 12.4 1.0
O B:GLN58 4.2 6.5 1.0
CA B:ILE59 4.3 6.9 1.0
CB B:ASN60 4.4 8.4 1.0
O B:HOH310 4.4 13.1 1.0
CZ2 B:TRP109 4.6 4.0 1.0
O B:HOH388 4.7 27.9 1.0
C B:ILE59 4.7 11.1 1.0
CG B:TRP109 4.7 6.2 1.0
CE2 B:TRP64 4.7 6.5 1.0
CD2 B:TRP109 4.8 5.3 1.0
CA B:ASN60 4.9 10.5 1.0
O B:ALA108 4.9 8.0 1.0
CG2 B:VAL99 4.9 7.2 1.0
CG2 B:ILE59 4.9 9.1 1.0
CG B:TRP64 4.9 8.3 1.0
CB B:ALA108 5.0 10.3 1.0
CB B:ILE59 5.0 7.0 1.0

Reference:

M.Oszajca, K.Kurpiewska, P.Halajko, A.Szura, K.Lewinski, M.Brindell. Ligand-Dependent Interaction of Anticancer Ruthenium Complexes with Hen Egg White Lysozyme and Human Lysozyme To Be Published.
Page generated: Sat Jul 12 05:10:06 2025

Last articles

Cu in 1AVL
Cu in 1AV4
Cu in 1AS7
Cu in 1AS8
Cu in 1AS6
Cu in 1AQS
Cu in 1AQR
Cu in 1AR1
Cu in 1ARM
Cu in 1AOZ
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy