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Chlorine in PDB 5lxm: Crystal Structure of Aurora-A Bound to A Hydrocarbon-Stapled Proteomimetic of TPX2
Enzymatic activity of Crystal Structure of Aurora-A Bound to A Hydrocarbon-Stapled Proteomimetic of TPX2
All present enzymatic activity of Crystal Structure of Aurora-A Bound to A Hydrocarbon-Stapled Proteomimetic of TPX2:
2.7.11.1;
2.7.11.1;
Protein crystallography data
The structure of Crystal Structure of Aurora-A Bound to A Hydrocarbon-Stapled Proteomimetic of TPX2, PDB code: 5lxm
was solved by
P.J.Mcintyre,
R.Bayliss,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 61.98 / 2.08 |
| Space group | P 31 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 79.780, 79.780, 140.260, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 20 / 24.3 |
Other elements in 5lxm:
The structure of Crystal Structure of Aurora-A Bound to A Hydrocarbon-Stapled Proteomimetic of TPX2 also contains other interesting chemical elements:
| Magnesium | (Mg) | 2 atoms |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Aurora-A Bound to A Hydrocarbon-Stapled Proteomimetic of TPX2
(pdb code 5lxm). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Aurora-A Bound to A Hydrocarbon-Stapled Proteomimetic of TPX2, PDB code: 5lxm:
In total only one binding site of Chlorine was determined in the Crystal Structure of Aurora-A Bound to A Hydrocarbon-Stapled Proteomimetic of TPX2, PDB code: 5lxm:
Chlorine binding site 1 out of 1 in 5lxm
Go back to
Chlorine Binding Sites List in 5lxm
Chlorine binding site 1 out
of 1 in the Crystal Structure of Aurora-A Bound to A Hydrocarbon-Stapled Proteomimetic of TPX2
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Crystal Structure of Aurora-A Bound to A Hydrocarbon-Stapled Proteomimetic of TPX2 within 5.0Å range:
|
Reference:
Y.K.Rennie,
P.J.Mcintyre,
T.Akindele,
R.Bayliss,
A.G.Jamieson.
A TPX2 Proteomimetic Has Enhanced Affinity For Aurora-A Due to Hydrocarbon Stapling of A Helix. Acs Chem. Biol. V. 11 3383 2016.
ISSN: ESSN 1554-8937
PubMed: 27775325
DOI: 10.1021/ACSCHEMBIO.6B00727
Page generated: Sat Jul 12 05:12:14 2025
ISSN: ESSN 1554-8937
PubMed: 27775325
DOI: 10.1021/ACSCHEMBIO.6B00727
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