Atomistry » Chlorine » PDB 5nke-5nry » 5nkp
Atomistry »
  Chlorine »
    PDB 5nke-5nry »
      5nkp »

Chlorine in PDB 5nkp: Crystal Structure of the Human KLHL3 Kelch Domain in Complex with A WNK3 Peptide

Enzymatic activity of Crystal Structure of the Human KLHL3 Kelch Domain in Complex with A WNK3 Peptide

All present enzymatic activity of Crystal Structure of the Human KLHL3 Kelch Domain in Complex with A WNK3 Peptide:
2.7.11.1;

Protein crystallography data

The structure of Crystal Structure of the Human KLHL3 Kelch Domain in Complex with A WNK3 Peptide, PDB code: 5nkp was solved by Z.Chen, F.J.Sorrell, D.M.Pinkas, E.Williams, S.Mathea, S.Goubin, F.Vondelft, C.H.Arrowsmith, A.M.Edwards, N.Burgess-Brown, C.Bountra, A.Bullock, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.03 / 2.80
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 84.660, 169.720, 123.860, 90.00, 90.00, 90.00
R / Rfree (%) 22.9 / 24.7

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of the Human KLHL3 Kelch Domain in Complex with A WNK3 Peptide (pdb code 5nkp). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of the Human KLHL3 Kelch Domain in Complex with A WNK3 Peptide, PDB code: 5nkp:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in 5nkp

Go back to Chlorine Binding Sites List in 5nkp
Chlorine binding site 1 out of 3 in the Crystal Structure of the Human KLHL3 Kelch Domain in Complex with A WNK3 Peptide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Human KLHL3 Kelch Domain in Complex with A WNK3 Peptide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl602

b:33.5
occ:1.00
OG A:SER385 2.9 33.0 1.0
NH1 A:ARG339 3.1 34.2 1.0
CB A:SER385 3.4 32.8 1.0
NE A:ARG360 3.6 34.0 1.0
NH2 A:ARG360 3.6 34.6 1.0
CD A:ARG339 3.6 33.7 1.0
CG2 A:THR386 3.7 33.3 1.0
CG2 D:THR541 3.9 34.2 1.0
CD2 A:PHE402 3.9 34.1 1.0
CA D:THR541 4.0 34.5 1.0
CZ A:ARG360 4.0 34.5 1.0
CB A:PHE402 4.1 33.4 1.0
CZ A:ARG339 4.1 34.3 1.0
CB D:THR541 4.2 34.3 1.0
C A:SER385 4.3 32.6 1.0
NE A:ARG339 4.3 34.1 1.0
OG1 A:THR386 4.4 33.1 1.0
CA A:SER385 4.5 32.5 1.0
CG A:PHE402 4.5 33.9 1.0
O A:SER385 4.5 32.6 1.0
N A:THR386 4.6 32.6 1.0
CB A:THR386 4.6 33.1 1.0
CG A:ARG360 4.6 33.4 1.0
CD A:ARG360 4.7 33.9 1.0
O D:GLU540 4.7 35.0 1.0
N D:GLU542 4.8 34.6 1.0
N D:THR541 4.8 34.8 1.0
CG A:ARG339 4.9 33.6 1.0
C D:THR541 4.9 34.8 1.0
CE2 A:PHE402 4.9 34.7 1.0
CB A:ARG339 5.0 33.2 1.0

Chlorine binding site 2 out of 3 in 5nkp

Go back to Chlorine Binding Sites List in 5nkp
Chlorine binding site 2 out of 3 in the Crystal Structure of the Human KLHL3 Kelch Domain in Complex with A WNK3 Peptide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the Human KLHL3 Kelch Domain in Complex with A WNK3 Peptide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl603

b:36.7
occ:1.00
O A:SER548 3.8 38.3 1.0
OD1 A:ASN550 3.8 37.0 1.0
OD1 A:ASP545 3.9 36.5 1.0
CG A:ASP545 4.0 36.4 1.0
C A:SER548 4.1 38.3 1.0
CB A:ASP545 4.2 37.0 1.0
O A:GLY547 4.3 37.3 1.0
NH2 A:ARG528 4.3 35.9 1.0
C A:GLY547 4.3 37.4 1.0
N A:SER548 4.4 37.8 1.0
OD2 A:ASP545 4.5 36.0 1.0
CA A:SER548 4.5 38.2 1.0
N A:CYS549 4.8 38.5 1.0
CG A:ASN550 4.8 37.5 1.0

Chlorine binding site 3 out of 3 in 5nkp

Go back to Chlorine Binding Sites List in 5nkp
Chlorine binding site 3 out of 3 in the Crystal Structure of the Human KLHL3 Kelch Domain in Complex with A WNK3 Peptide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of the Human KLHL3 Kelch Domain in Complex with A WNK3 Peptide within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl601

b:31.3
occ:1.00
OG B:SER385 2.6 31.7 1.0
NH1 B:ARG339 3.1 31.7 1.0
CB B:SER385 3.2 31.7 1.0
NE B:ARG360 3.5 31.9 1.0
CD B:ARG339 3.7 31.7 1.0
CG2 B:THR386 3.7 30.9 1.0
NH2 B:ARG360 3.7 31.8 1.0
CD2 B:PHE402 3.9 30.9 1.0
CZ B:ARG360 4.0 32.0 1.0
CG2 C:THR541 4.0 31.0 1.0
CZ B:ARG339 4.2 31.8 1.0
CA C:THR541 4.3 31.0 1.0
C B:SER385 4.3 31.3 1.0
CG B:ARG360 4.3 32.2 1.0
NE B:ARG339 4.4 31.8 1.0
CA B:SER385 4.4 31.7 1.0
CB C:THR541 4.5 30.9 1.0
CD B:ARG360 4.5 32.3 1.0
CB B:PHE402 4.5 30.6 1.0
OG1 B:THR386 4.6 30.7 1.0
N B:THR386 4.6 31.4 1.0
O B:SER385 4.6 31.1 1.0
CE2 B:PHE402 4.7 31.0 1.0
CG B:PHE402 4.7 30.6 1.0
CB B:THR386 4.7 30.9 1.0
CD1 B:PHE355 4.8 32.9 1.0
CG B:ARG339 4.9 31.9 1.0
O C:GLU540 4.9 31.5 1.0
CB B:ARG339 4.9 32.0 1.0
N C:THR541 4.9 31.3 1.0
CG B:PHE355 5.0 32.9 1.0
O B:PHE402 5.0 31.3 1.0
CB B:PHE355 5.0 32.9 1.0

Reference:

Z.Chen, F.J.Sorrell, D.M.Pinkas, E.Williams, S.Mathea, S.Goubin, F.Von Delft, C.H.Arrowsmith, A.M.Edwards, N.Burgess-Brown, C.Bountra, A.Bullock. Crystal Structure of the Human KLHL3 Kelch Domain in Complex with A WNK3 Peptide To Be Published.
Page generated: Sat Jul 12 06:11:44 2025

Last articles

Cu in 5X1B
Cu in 5X31
Cu in 5X19
Cu in 5WEH
Cu in 5WSZ
Cu in 5WJA
Cu in 5WBD
Cu in 5UE6
Cu in 5WAU
Cu in 5W97
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy