Atomistry » Chlorine » PDB 5s33-5sdc » 5sbd
Atomistry »
  Chlorine »
    PDB 5s33-5sdc »
      5sbd »

Chlorine in PDB 5sbd: Tubulin-Maytansinoid-5B-Complex

Protein crystallography data

The structure of Tubulin-Maytansinoid-5B-Complex, PDB code: 5sbd was solved by P.Marzullo, Z.Boiarska, H.Perez-Pena, A.-C.Abel, B.Alvarez-Bernad, D.Lucena-Agell, F.Vasile, M.Sironi, M.O.Steinmetz, A.E.Prota, J.F.Diaz, S.Pieraccini, D.Passarella, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 49.58 / 2.25
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 105.075, 158.601, 180.439, 90, 90, 90
R / Rfree (%) 17.9 / 21.4

Other elements in 5sbd:

The structure of Tubulin-Maytansinoid-5B-Complex also contains other interesting chemical elements:

Magnesium (Mg) 5 atoms
Calcium (Ca) 4 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Tubulin-Maytansinoid-5B-Complex (pdb code 5sbd). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Tubulin-Maytansinoid-5B-Complex, PDB code: 5sbd:

Chlorine binding site 1 out of 1 in 5sbd

Go back to Chlorine Binding Sites List in 5sbd
Chlorine binding site 1 out of 1 in the Tubulin-Maytansinoid-5B-Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Tubulin-Maytansinoid-5B-Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl503

b:82.8
occ:1.00
CL33 D:5KI503 0.0 82.8 1.0
C6 D:5KI503 1.8 81.5 1.0
C1 D:5KI503 2.7 86.1 1.0
C5 D:5KI503 2.8 76.0 1.0
O34 D:5KI503 2.9 69.5 1.0
N31 D:5KI503 3.2 83.3 1.0
CZ D:PHE404 3.5 83.5 1.0
C36 D:5KI503 3.7 74.6 1.0
C35 D:5KI503 3.8 67.5 1.0
CG2 D:VAL181 3.8 75.3 1.0
C28 D:5KI503 3.8 76.3 1.0
CE2 D:PHE404 4.0 77.1 1.0
C2 D:5KI503 4.1 75.2 1.0
C4 D:5KI503 4.1 81.1 1.0
C27 D:5KI503 4.1 63.7 1.0
CG1 D:VAL181 4.4 62.7 1.0
CE1 D:PHE404 4.4 81.5 1.0
C3 D:5KI503 4.6 76.2 1.0
O32 D:5KI503 4.7 77.8 1.0
CB D:VAL181 4.8 66.0 1.0

Reference:

P.Marzullo, Z.Boiarska, H.Perez-Pena, A.C.Abel, B.Alvarez-Bernad, D.Lucena-Agell, F.Vasile, M.Sironi, K.H.Altmann, A.E.Prota, J.F.Diaz, S.Pieraccini, D.Passarella. Maytansinol Derivatives: Side Reactions As A Chance For New Tubulin Binders. Chemistry 2021.
ISSN: ISSN 0947-6539
PubMed: 34788896
DOI: 10.1002/CHEM.202103520
Page generated: Fri Jul 26 16:41:43 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy