Atomistry » Chlorine » PDB 5s33-5sdc » 5sd0
Atomistry »
  Chlorine »
    PDB 5s33-5sdc »
      5sd0 »

Chlorine in PDB 5sd0: Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis Bound to Nadp and Sddc Inhibitor Sddc-1225

Enzymatic activity of Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis Bound to Nadp and Sddc Inhibitor Sddc-1225

All present enzymatic activity of Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis Bound to Nadp and Sddc Inhibitor Sddc-1225:
1.5.1.3;

Protein crystallography data

The structure of Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis Bound to Nadp and Sddc Inhibitor Sddc-1225, PDB code: 5sd0 was solved by Seattle Structural Genomics Center For Infectious Disease (Ssgcid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 49.14 / 1.75
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 29.48, 67.13, 72.14, 90, 90, 90
R / Rfree (%) 14.5 / 18.6

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis Bound to Nadp and Sddc Inhibitor Sddc-1225 (pdb code 5sd0). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis Bound to Nadp and Sddc Inhibitor Sddc-1225, PDB code: 5sd0:

Chlorine binding site 1 out of 1 in 5sd0

Go back to Chlorine Binding Sites List in 5sd0
Chlorine binding site 1 out of 1 in the Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis Bound to Nadp and Sddc Inhibitor Sddc-1225


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis Bound to Nadp and Sddc Inhibitor Sddc-1225 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl203

b:24.4
occ:1.00
 O A:HOH442 3.1 34.2 1.0
NH2 A:ARG60 3.2 17.1 1.0
NH1 A:ARG60 3.3 15.7 1.0
CE2 A:PHE31 3.6 15.2 1.0
CG A:ARG32 3.6 18.8 1.0
NE A:ARG32 3.7 35.7 1.0
CZ A:ARG60 3.7 18.1 1.0
CD2 A:PHE31 3.8 14.7 1.0
NE2 A:GLN28 3.9 36.0 1.0
O A:HOH308 4.0 40.4 1.0
CZ A:ARG32 4.0 43.6 1.0
NH2 A:ARG32 4.1 40.4 1.0
C19 A:HIK202 4.2 21.8 0.7
CD1 A:LEU57 4.2 14.7 1.0
C20 A:HIK202 4.2 29.0 0.3
CD A:ARG32 4.3 26.3 1.0
C19 A:HIK202 4.3 23.6 0.3
O21 A:HIK202 4.6 31.5 0.7
CD2 A:LEU57 4.7 17.2 1.0
CG A:GLN28 4.7 31.3 1.0
NH1 A:ARG32 4.7 46.4 1.0
CB A:LEU57 4.8 12.5 1.0
CG A:LEU57 4.8 16.4 1.0
C18 A:HIK202 4.8 20.6 0.7
CZ A:PHE31 4.8 15.2 1.0
C18 A:HIK202 4.8 21.6 0.3
CD A:GLN28 4.9 35.5 1.0
CB A:ARG32 4.9 16.6 1.0
C20 A:HIK202 5.0 30.1 0.7

Reference:

S.J.Mayclin, J.W.Fairman, D.M.Dranow, D.G.Conrady, D.Fox Iii, C.M.Lukacs, D.D.Lorimer, P.S.Horanyi, T.E.Edwards, J.Abendroth. Crystal Structure of Dihydrofolate Reductase From Mycobacterium Tuberculosis Bound to Nadp and Sddc Inhibitor Sddc-1225 To Be Published.
Page generated: Fri Jul 26 16:42:25 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy