Chlorine in PDB 5uhr: Crystal Structure of (Cit)Lanflv Heptapeptide Segment From Islet Amyloid Polypeptide (Iapp) Incorporated Into A Macrocyclic Beta-Sheet Template

The structure of Crystal Structure of (Cit)Lanflv Heptapeptide Segment From Islet Amyloid Polypeptide (Iapp) Incorporated Into A Macrocyclic Beta-Sheet Template, PDB code: 5uhr was solved by Y.Wang, A.G.Kreutzer, J.S.Nowick, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.96 / 1.80
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	33.876, 33.876, 99.054, 90.00, 90.00, 90.00
R / Rfree (%)	21.9 / 26.5

The structure of Crystal Structure of (Cit)Lanflv Heptapeptide Segment From Islet Amyloid Polypeptide (Iapp) Incorporated Into A Macrocyclic Beta-Sheet Template also contains other interesting chemical elements:

Bromine

(Br)

4 atoms

The binding sites of Chlorine atom in the Crystal Structure of (Cit)Lanflv Heptapeptide Segment From Islet Amyloid Polypeptide (Iapp) Incorporated Into A Macrocyclic Beta-Sheet Template (pdb code 5uhr). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of (Cit)Lanflv Heptapeptide Segment From Islet Amyloid Polypeptide (Iapp) Incorporated Into A Macrocyclic Beta-Sheet Template, PDB code: 5uhr:

Chlorine binding site 1 out of 1 in the Crystal Structure of (Cit)Lanflv Heptapeptide Segment From Islet Amyloid Polypeptide (Iapp) Incorporated Into A Macrocyclic Beta-Sheet Template


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of (Cit)Lanflv Heptapeptide Segment From Islet Amyloid Polypeptide (Iapp) Incorporated Into A Macrocyclic Beta-Sheet Template within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl101 b:71.8 occ:1.00 HZ3 B:LYS11 2.7 48.8 1.0 HZ2 B:LYS11 3.3 48.8 1.0 NZ B:LYS11 3.4 40.6 1.0 O B:HOH209 3.6 52.9 1.0 HZ1 B:LYS11 3.8 48.8 1.0 HD2 B:LYS11 4.0 39.1 1.0 O B:ORN9 4.4 24.8 1.0 HG3 B:LYS11 4.4 33.2 1.0 CE B:LYS11 4.6 36.9 1.0 CD B:LYS11 4.6 32.5 1.0 HB2 B:LYS11 4.7 29.0 1.0 HE2 B:LYS11 4.9 44.3 1.0 CG B:LYS11 5.0 27.6 1.0

Y.Wang, A.G.Kreutzer, N.L.Truex, J.S.Nowick. A Tetramer Derived From Islet Amyloid Polypeptide. J. Org. Chem. V. 82 7905 2017.
ISSN: ISSN 1520-6904
PubMed: 28661686
DOI: 10.1021/ACS.JOC.7B01116