Chlorine in PDB 5uqs: Crystal Structure of Citrate Synthase From Sus Scrofa

All present enzymatic activity of Crystal Structure of Citrate Synthase From Sus Scrofa:
2.3.3.1;

The structure of Crystal Structure of Citrate Synthase From Sus Scrofa, PDB code: 5uqs was solved by C.Schlachter, M.Chruszcz, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	34.00 / 1.60
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	58.575, 59.884, 74.761, 99.60, 98.47, 117.53
R / Rfree (%)	15.3 / 17.8

The binding sites of Chlorine atom in the Crystal Structure of Citrate Synthase From Sus Scrofa (pdb code 5uqs). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Citrate Synthase From Sus Scrofa, PDB code: 5uqs:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Citrate Synthase From Sus Scrofa


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Citrate Synthase From Sus Scrofa within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl501 b:20.7 occ:1.00 O A:HOH991 2.9 22.4 1.0 O A:HOH952 3.1 35.1 1.0 NH1 A:ARG428 3.1 11.1 1.0 O A:HOH776 3.3 19.1 0.5 NH2 A:ARG428 3.5 11.5 1.0 CE1 A:HIS301 3.7 15.7 1.0 CZ A:ARG428 3.8 11.0 1.0 CG A:ASN269 3.9 10.3 1.0 CB A:ASN269 3.9 10.2 1.0 ND2 A:ASN269 4.0 11.2 1.0 CZ A:PHE424 4.0 15.6 1.0 CB A:HIS265 4.1 11.5 1.0 OD1 A:ASN269 4.3 10.9 1.0 ND1 A:HIS301 4.5 15.8 1.0 CE1 A:PHE424 4.7 15.5 1.0 CG A:HIS265 4.7 13.2 1.0 NE2 A:HIS301 4.7 14.2 1.0 O A:HOH1068 4.9 44.0 1.0 O A:HIS265 5.0 9.4 1.0 O A:HOH905 5.0 27.7 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Citrate Synthase From Sus Scrofa


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Citrate Synthase From Sus Scrofa within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl501 b:25.1 occ:1.00 O C:HOH874 2.5 36.7 1.0 O C:HOH947 2.9 17.8 0.5 O C:HOH971 2.9 28.8 1.0 NH1 C:ARG428 3.1 12.6 1.0 NH2 C:ARG428 3.5 12.6 1.0 CZ C:ARG428 3.8 12.3 1.0 CE1 C:HIS301 3.8 16.4 1.0 CG C:ASN269 3.9 10.7 1.0 CB C:ASN269 4.0 10.9 1.0 CB C:HIS265 4.0 12.4 1.0 CZ C:PHE424 4.0 16.2 1.0 ND2 C:ASN269 4.0 10.9 1.0 OD1 C:ASN269 4.3 11.2 1.0 O C:HOH892 4.4 26.3 0.5 O C:HOH816 4.4 39.3 1.0 ND1 C:HIS301 4.6 16.9 1.0 CG C:HIS265 4.6 13.8 1.0 CE1 C:PHE424 4.7 16.5 1.0 NE2 C:HIS301 4.8 15.4 1.0 O C:HOH882 5.0 30.1 1.0 O C:HIS265 5.0 10.0 1.0

C.Schlachter, M.Chruszcz. Structural and Functional Characterization of 2-Methylcitrate Synthase (Mcsa) From Aspergillus Fumigatus and Citrate Synthase (Hcs) From Homo Sapiens. To Be Published.