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Chlorine in PDB 5v6z: Crystal Structure of Human Caspase-7 Soaked with Allosteric Inhibitor 2-{[2-(4-Chlorophenyl)-2-Oxoethyl]Sulfanyl}Benzoic Acid

Enzymatic activity of Crystal Structure of Human Caspase-7 Soaked with Allosteric Inhibitor 2-{[2-(4-Chlorophenyl)-2-Oxoethyl]Sulfanyl}Benzoic Acid

All present enzymatic activity of Crystal Structure of Human Caspase-7 Soaked with Allosteric Inhibitor 2-{[2-(4-Chlorophenyl)-2-Oxoethyl]Sulfanyl}Benzoic Acid:
3.4.22.60;

Protein crystallography data

The structure of Crystal Structure of Human Caspase-7 Soaked with Allosteric Inhibitor 2-{[2-(4-Chlorophenyl)-2-Oxoethyl]Sulfanyl}Benzoic Acid, PDB code: 5v6z was solved by N.R.Vance, L.Gakhar, M.A.Spies, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 59.34 / 2.60
Space group P 32 2 1
Cell size a, b, c (Å), α, β, γ (°) 89.344, 89.344, 184.898, 90.00, 90.00, 120.00
R / Rfree (%) 20.5 / 24.9

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Human Caspase-7 Soaked with Allosteric Inhibitor 2-{[2-(4-Chlorophenyl)-2-Oxoethyl]Sulfanyl}Benzoic Acid (pdb code 5v6z). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human Caspase-7 Soaked with Allosteric Inhibitor 2-{[2-(4-Chlorophenyl)-2-Oxoethyl]Sulfanyl}Benzoic Acid, PDB code: 5v6z:

Chlorine binding site 1 out of 1 in 5v6z

Go back to Chlorine Binding Sites List in 5v6z
Chlorine binding site 1 out of 1 in the Crystal Structure of Human Caspase-7 Soaked with Allosteric Inhibitor 2-{[2-(4-Chlorophenyl)-2-Oxoethyl]Sulfanyl}Benzoic Acid


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human Caspase-7 Soaked with Allosteric Inhibitor 2-{[2-(4-Chlorophenyl)-2-Oxoethyl]Sulfanyl}Benzoic Acid within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl401

b:0.8
occ:0.69
CLA B:8YJ401 0.0 0.8 0.7
CAM B:8YJ401 1.8 89.2 0.7
CAL B:8YJ401 2.7 89.5 0.7
CAN B:8YJ401 2.7 86.7 0.7
CAK B:8YJ401 4.0 90.7 0.7
CAO B:8YJ401 4.0 81.3 0.7
CB B:ASN148 4.4 47.1 1.0
CAJ B:8YJ401 4.5 84.1 0.7

Reference:

N.R.Vance, L.Gakhar, M.A.Spies. Crystal Structure of Human Caspase-7 Soaked with Allosteric Inhibitor To Be Published.
Page generated: Sat Jul 12 09:44:59 2025

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