Chlorine in PDB 5wu2: Crystal Structure of Human TUT1 Bound with Bautp, Form I

All present enzymatic activity of Crystal Structure of Human TUT1 Bound with Bautp, Form I:
2.7.7.19; 2.7.7.52;

The structure of Crystal Structure of Human TUT1 Bound with Bautp, Form I, PDB code: 5wu2 was solved by S.Yamashita, K.Tomita, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.94 / 2.95
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	77.330, 88.400, 184.190, 90.00, 90.00, 90.00
R / Rfree (%)	24.6 / 29.4

The structure of Crystal Structure of Human TUT1 Bound with Bautp, Form I also contains other interesting chemical elements:

Barium

(Ba)

2 atoms

The binding sites of Chlorine atom in the Crystal Structure of Human TUT1 Bound with Bautp, Form I (pdb code 5wu2). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Human TUT1 Bound with Bautp, Form I, PDB code: 5wu2:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Human TUT1 Bound with Bautp, Form I


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human TUT1 Bound with Bautp, Form I within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1003 b:70.6 occ:1.00 NE1 A:TRP505 3.1 46.1 1.0 NH1 A:ARG445 3.6 56.1 1.0 CD1 A:TRP505 4.0 47.5 1.0 CB A:ALA501 4.0 39.4 1.0 CE2 A:TRP505 4.2 39.9 1.0 NH2 A:ARG445 4.2 43.1 1.0 CA A:ALA501 4.4 49.0 1.0 CZ A:ARG445 4.4 50.3 1.0 CZ2 A:TRP505 4.6 38.9 1.0 OG A:SER504 4.7 62.3 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Human TUT1 Bound with Bautp, Form I


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Human TUT1 Bound with Bautp, Form I within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1003 b:68.0 occ:1.00 NE1 B:TRP505 3.1 56.1 1.0 NH1 B:ARG445 3.3 51.3 1.0 CB B:ALA501 3.9 47.4 1.0 CD1 B:TRP505 4.1 54.9 1.0 NH2 B:ARG445 4.1 64.0 1.0 CE2 B:TRP505 4.1 51.4 1.0 CZ B:ARG445 4.2 56.0 1.0 CZ2 B:TRP505 4.4 52.9 1.0 CA B:ALA501 4.5 44.7 1.0

S.Yamashita, Y.Takagi, T.Nagaike, K.Tomita. Crystal Structures of U6 Snrna-Specific Terminal Uridylyltransferase Nat Commun V. 8 15788 2017.
ISSN: ESSN 2041-1723
PubMed: 28589955
DOI: 10.1038/NCOMMS15788