Chlorine in PDB 5x08: Crystal Structure of Broadly Neutralizing Anti-Hiv-1 Antibody 4E10, Mutant Npro, with Peptide Bound

The structure of Crystal Structure of Broadly Neutralizing Anti-Hiv-1 Antibody 4E10, Mutant Npro, with Peptide Bound, PDB code: 5x08 was solved by J.M.M.Caaveiro, E.Rujas, J.L.Nieva, K.Tsumoto, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	22.25 / 1.49
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	157.509, 44.500, 85.130, 90.00, 113.70, 90.00
R / Rfree (%)	12.9 / 16.9

The binding sites of Chlorine atom in the Crystal Structure of Broadly Neutralizing Anti-Hiv-1 Antibody 4E10, Mutant Npro, with Peptide Bound (pdb code 5x08). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Broadly Neutralizing Anti-Hiv-1 Antibody 4E10, Mutant Npro, with Peptide Bound, PDB code: 5x08:

Chlorine binding site 1 out of 1 in the Crystal Structure of Broadly Neutralizing Anti-Hiv-1 Antibody 4E10, Mutant Npro, with Peptide Bound


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Broadly Neutralizing Anti-Hiv-1 Antibody 4E10, Mutant Npro, with Peptide Bound within 5.0Å range: probe atom residue distance (Å) B Occ L:Cl303 b:24.1 occ:1.00 O L:HOH595 3.0 20.2 1.0 O L:HOH403 3.0 24.6 0.5 N L:ALA59 3.1 13.0 1.0 NH2 L:ARG45 3.2 19.4 1.0 NH1 L:ARG45 3.4 18.2 1.0 CZ L:ARG45 3.7 17.1 1.0 CB L:ALA59 3.7 14.7 1.0 CA L:VAL58 3.9 13.5 1.0 CE2 L:PHE62 3.9 17.1 1.0 C L:VAL58 4.0 12.4 1.0 CA L:ALA59 4.0 12.9 1.0 CG1 L:VAL58 4.2 13.1 1.0 CD2 L:PHE62 4.2 13.9 1.0 O L:GLY57 4.3 23.5 1.0 CB L:VAL58 4.5 12.3 1.0 O L:HOH461 4.8 15.3 1.0 CG2 L:VAL58 4.9 15.8 1.0 O L:HOH407 4.9 29.4 1.0 CD2 L:LEU47 4.9 15.0 1.0 CZ L:PHE62 5.0 15.8 1.0 N L:VAL58 5.0 16.1 1.0

E.Rujas, S.Insausti, M.Garcia-Porras, R.Sanchez-Eugenia, K.Tsumoto, J.L.Nieva, J.M.M.Caaveiro. Functional Contacts Between Mper and the Anti-Hiv-1 Broadly Neutralizing Antibody 4E10 Extend Into the Core of the Membrane J. Mol. Biol. V. 429 1213 2017.
ISSN: ESSN 1089-8638
PubMed: 28300601
DOI: 10.1016/J.JMB.2017.03.008