Chlorine in PDB 5y16: Crystal Structure of Human DUSP28(Y102H)

All present enzymatic activity of Crystal Structure of Human DUSP28(Y102H):
3.1.3.16; 3.1.3.48;

The structure of Crystal Structure of Human DUSP28(Y102H), PDB code: 5y16 was solved by B.Ku, M.Kim, S.J.Kim, S.E.Ryu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.63 / 2.40
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	79.341, 79.341, 90.549, 90.00, 90.00, 120.00
R / Rfree (%)	18.7 / 24

The binding sites of Chlorine atom in the Crystal Structure of Human DUSP28(Y102H) (pdb code 5y16). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of Human DUSP28(Y102H), PDB code: 5y16:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Crystal Structure of Human DUSP28(Y102H)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human DUSP28(Y102H) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl202 b:34.8 occ:1.00 NH1 A:ARG109 3.2 29.9 1.0 N A:GLN54 3.2 34.6 1.0 N A:ARG53 3.3 36.7 1.0 CD1 A:PHE71 3.5 35.6 1.0 CB A:SER52 3.6 30.5 1.0 CG A:GLN54 3.6 35.7 1.0 CB A:GLN54 3.7 38.1 1.0 CE1 A:PHE71 3.8 43.0 1.0 CA A:GLN54 4.0 33.9 1.0 CA A:SER52 4.0 32.0 1.0 CA A:ARG53 4.0 35.0 1.0 C A:ARG53 4.1 32.1 1.0 C A:SER52 4.1 30.5 1.0 CB A:ARG53 4.1 34.9 1.0 CZ A:ARG109 4.2 34.2 1.0 NH2 A:ARG109 4.2 28.9 1.0 O A:VAL70 4.2 33.6 1.0 OG A:SER52 4.4 32.0 1.0 N A:GLN55 4.4 34.7 1.0 C A:GLN54 4.6 32.7 1.0 CA A:PHE71 4.6 33.8 1.0 CG A:PHE71 4.7 39.5 1.0 CG A:GLN55 4.7 30.6 1.0 CG A:ARG53 4.9 33.9 1.0 CD A:GLN54 4.9 38.0 1.0 OE1 A:GLN55 5.0 37.9 1.0 C A:VAL70 5.0 32.7 1.0

Chlorine binding site 2 out of 3 in the Crystal Structure of Human DUSP28(Y102H)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Human DUSP28(Y102H) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl202 b:86.6 occ:1.00 NZ B:LYS134 3.6 91.9 1.0 CE2 B:PHE130 3.7 75.0 1.0 CZ B:PHE130 4.3 63.0 1.0 CE B:LYS134 4.7 76.6 1.0 CD2 B:PHE130 4.8 67.0 1.0 CE3 B:TRP147 4.9 65.1 1.0

Chlorine binding site 3 out of 3 in the Crystal Structure of Human DUSP28(Y102H)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Human DUSP28(Y102H) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl203 b:69.5 occ:1.00 O B:HOH317 3.5 56.0 1.0 O B:GLY123 4.0 61.3 1.0 N B:SER125 4.2 52.8 1.0 O B:HOH312 4.3 52.9 1.0 C B:LEU124 4.4 51.1 1.0 C B:GLY123 4.7 49.7 1.0 CA B:SER125 4.7 50.3 1.0 CB B:SER125 4.8 44.1 1.0 O B:LEU124 4.8 45.8 1.0 CA B:LEU124 4.8 46.6 1.0

B.Ku, W.Hong, C.W.Keum, M.Kim, H.Ryu, D.Jeon, H.C.Shin, J.H.Kim, S.J.Kim, S.E.Ryu. Structural and Biochemical Analysis of Atypically Low Dephosphorylating Activity of Human Dual-Specificity Phosphatase 28 Plos One V. 12 87701 2017.
ISSN: ESSN 1932-6203
PubMed: 29121083
DOI: 10.1371/JOURNAL.PONE.0187701