Atomistry » Chlorine » PDB 5z42-5zkn » 5zeq
Atomistry »
  Chlorine »
    PDB 5z42-5zkn »
      5zeq »

Chlorine in PDB 5zeq: Carboxypeptidase B in Complex with DD28

Enzymatic activity of Carboxypeptidase B in Complex with DD28

All present enzymatic activity of Carboxypeptidase B in Complex with DD28:
3.4.17.2;

Protein crystallography data

The structure of Carboxypeptidase B in Complex with DD28, PDB code: 5zeq was solved by T.Itoh, N.Yoshimoto, K.Yamamoto, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 48.71 / 1.90
Space group P 41 21 2
Cell size a, b, c (Å), α, β, γ (°) 78.860, 78.860, 100.040, 90.00, 90.00, 90.00
R / Rfree (%) 15.2 / 20.4

Other elements in 5zeq:

The structure of Carboxypeptidase B in Complex with DD28 also contains other interesting chemical elements:

Zinc (Zn) 7 atoms
Arsenic (As) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Carboxypeptidase B in Complex with DD28 (pdb code 5zeq). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Carboxypeptidase B in Complex with DD28, PDB code: 5zeq:

Chlorine binding site 1 out of 1 in 5zeq

Go back to Chlorine Binding Sites List in 5zeq
Chlorine binding site 1 out of 1 in the Carboxypeptidase B in Complex with DD28


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Carboxypeptidase B in Complex with DD28 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl406

b:27.6
occ:1.00
CL1 A:9B3406 0.0 27.6 1.0
C2 A:9B3406 1.7 27.0 1.0
C1 A:9B3406 2.6 28.7 1.0
C3 A:9B3406 2.7 28.8 1.0
N1 A:9B3406 2.9 27.1 1.0
O A:ASN144 3.2 13.3 1.0
CB A:ALA250 3.3 15.8 1.0
NH1 A:ARG145 3.4 11.2 1.0
O A:ALA250 3.4 16.8 1.0
O A:HOH644 3.5 13.1 1.0
CA A:GLY253 3.6 12.4 1.0
N A:GLY253 3.6 12.9 1.0
C A:ALA250 3.6 15.3 1.0
CZ A:ARG145 3.9 12.3 1.0
C5 A:9B3406 3.9 29.1 1.0
O A:ALA251 4.0 13.5 1.0
N2 A:9B3406 4.0 34.1 1.0
ND2 A:ASN144 4.0 12.7 1.0
CD A:ARG145 4.1 11.1 1.0
CA A:ALA250 4.1 16.0 1.0
NE A:ARG145 4.2 11.1 1.0
C A:ALA251 4.2 13.7 1.0
N A:ALA251 4.2 13.6 1.0
C4 A:9B3406 4.4 30.3 1.0
C A:ASN144 4.5 11.5 1.0
C A:GLY252 4.5 12.6 1.0
CG A:ASN144 4.5 11.8 1.0
CB A:SER207 4.5 14.2 1.0
O1 A:9B3406 4.6 16.5 1.0
O A:HOH623 4.6 22.7 1.0
CA A:ALA251 4.6 14.1 1.0
NH2 A:ARG145 4.7 11.6 1.0
N A:GLY252 4.7 12.4 1.0
OG A:SER207 4.9 14.4 1.0
OD1 A:ASN144 5.0 9.9 1.0
C A:GLY253 5.0 12.7 1.0

Reference:

T.Itoh, N.Yoshimoto, Y.Hirano, K.Yamamoto. Structural Basis For the Selective Inhibition of Activated Thrombin-Activatable Fibrinolysis Inhibitor (Tafia) By A Selenium-Containing Inhibitor with Chloro-Aminopyridine As A Basic Group Bioorg. Med. Chem. Lett. V. 28 2256 2018.
ISSN: ESSN 1464-3405
PubMed: 29859906
DOI: 10.1016/J.BMCL.2018.05.042
Page generated: Sat Jul 12 11:08:56 2025

Last articles

Cu in 4WKX
Cu in 4X27
Cu in 4WZ9
Cu in 4W9Z
Cu in 4W7R
Cu in 4WF5
Cu in 4WBR
Cu in 4W7F
Cu in 4W7D
Cu in 4W7E
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy