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Atomistry » Chlorine » PDB 6aqe-6axv » 6auu | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 6aqe-6axv » 6auu » |
Chlorine in PDB 6auu: Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(3-(3-(Dimethylamino)Propyl)-5-(Trifluoromethyl)Phenethyl)-4- Methylpyridin-2-AmineEnzymatic activity of Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(3-(3-(Dimethylamino)Propyl)-5-(Trifluoromethyl)Phenethyl)-4- Methylpyridin-2-Amine
All present enzymatic activity of Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(3-(3-(Dimethylamino)Propyl)-5-(Trifluoromethyl)Phenethyl)-4- Methylpyridin-2-Amine:
1.14.13.39; Protein crystallography data
The structure of Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(3-(3-(Dimethylamino)Propyl)-5-(Trifluoromethyl)Phenethyl)-4- Methylpyridin-2-Amine, PDB code: 6auu
was solved by
H.Li,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6auu:
The structure of Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(3-(3-(Dimethylamino)Propyl)-5-(Trifluoromethyl)Phenethyl)-4- Methylpyridin-2-Amine also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(3-(3-(Dimethylamino)Propyl)-5-(Trifluoromethyl)Phenethyl)-4- Methylpyridin-2-Amine
(pdb code 6auu). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(3-(3-(Dimethylamino)Propyl)-5-(Trifluoromethyl)Phenethyl)-4- Methylpyridin-2-Amine, PDB code: 6auu: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 6auuGo back to![]() ![]()
Chlorine binding site 1 out
of 2 in the Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(3-(3-(Dimethylamino)Propyl)-5-(Trifluoromethyl)Phenethyl)-4- Methylpyridin-2-Amine
![]() Mono view ![]() Stereo pair view
Chlorine binding site 2 out of 2 in 6auuGo back to![]() ![]()
Chlorine binding site 2 out
of 2 in the Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(3-(3-(Dimethylamino)Propyl)-5-(Trifluoromethyl)Phenethyl)-4- Methylpyridin-2-Amine
![]() Mono view ![]() Stereo pair view
Reference:
H.T.Do,
H.Y.Wang,
H.Li,
G.Chreifi,
T.L.Poulos,
R.B.Silverman.
Improvement of Cell Permeability of Human Neuronal Nitric Oxide Synthase Inhibitors Using Potent and Selective 2-Aminopyridine-Based Scaffolds with A Fluorobenzene Linker. J. Med. Chem. V. 60 9360 2017.
Page generated: Sat Jul 12 11:32:46 2025
ISSN: ISSN 1520-4804 PubMed: 29091437 DOI: 10.1021/ACS.JMEDCHEM.7B01356 |
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