Chlorine in PDB 6b20: Crystal Structure of A Complex Between G Protein Beta Gamma Dimer and An Inhibitory Nanobody Regulator

The structure of Crystal Structure of A Complex Between G Protein Beta Gamma Dimer and An Inhibitory Nanobody Regulator, PDB code: 6b20 was solved by S.Gulati, P.D.Kiser, K.Palczewski, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.82 / 2.34
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	72.660, 77.230, 101.660, 90.00, 109.80, 90.00
R / Rfree (%)	20 / 24.9

The binding sites of Chlorine atom in the Crystal Structure of A Complex Between G Protein Beta Gamma Dimer and An Inhibitory Nanobody Regulator (pdb code 6b20). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of A Complex Between G Protein Beta Gamma Dimer and An Inhibitory Nanobody Regulator, PDB code: 6b20:

Chlorine binding site 1 out of 1 in the Crystal Structure of A Complex Between G Protein Beta Gamma Dimer and An Inhibitory Nanobody Regulator


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of A Complex Between G Protein Beta Gamma Dimer and An Inhibitory Nanobody Regulator within 5.0Å range: probe atom residue distance (Å) B Occ E:Cl201 b:68.3 occ:1.00 CD E:ARG45 3.2 74.5 1.0 NH1 E:ARG45 3.4 71.0 1.0 CH2 E:TRP104 3.8 36.6 1.0 OG E:SER100 3.9 44.0 1.0 CZ2 E:TRP104 4.0 34.1 1.0 NE E:ARG45 4.1 72.9 1.0 O B:HOH546 4.1 50.0 1.0 CG E:ARG45 4.1 72.4 1.0 CZ E:ARG45 4.2 73.7 1.0 CB E:ARG45 4.2 69.2 1.0 OD2 B:ASP246 4.7 50.3 1.0 CE2 E:TYR37 4.8 46.0 1.0 CZ3 E:TRP104 4.9 37.5 1.0 CD2 E:TYR37 4.9 45.2 1.0

S.Gulati, H.Jin, I.Masuho, T.Orban, Y.Cai, E.Pardon, K.A.Martemyanov, P.D.Kiser, P.L.Stewart, C.P.Ford, J.Steyaert, K.Palczewski. Targeting G Protein-Coupled Receptor Signaling at the G Protein Level with A Selective Nanobody Inhibitor. Nat Commun V. 9 1996 2018.
ISSN: ESSN 2041-1723
PubMed: 29777099
DOI: 10.1038/S41467-018-04432-0